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This article suggests RNA Pol III formed early in eukaryote evolution, and while there's a lot of conservation, the enzyme-specific subunits result from divergent evolution. Another article suggests the actual increase of subunits, however, is a result of the permanent recruitment of transcription factors to the core RNAP by studying homology of subunits to ...


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The three RNA polymerases (RNAPs) are very similar to each other, yet not identical. As described in this article, there are subunits that are specific for each type of polymerases. In addition to providing unique substrates that polymerase-specific subunits bind to give each of the RNAPs their specific functionality, the two largest subunits also shape ...



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