New answers tagged senescence
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Following damage to muscle (e.g., as a result of strenuous activity) the injured fibers are removed (by immune cells) and then replaced by new myofibers (individual muscle cells that join to create new muscle tissue). This is why for a few days after exercise your muscles can be sore - it is the tissues being initially cleared of damaged cells and repaired.
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Telomerase activity is just one (probably minor) facet of aging. It takes a lot more than just basic end repair of DNA to keep a complex organism alive, especially mammals. Just a few issues off the top of my head:
repairing oxidative stress to DNA and proteins
repairing UV damage to DNA
keeping cells clean of debris like protein aggregate buildup (think ...
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