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we included a script to calculate this in supplemental material http://onlinelibrary.wiley.com/doi/10.1111/mec.13034/full ....single segregating site per locus or up to a maximum of four SNPs, as is expected for short-read genomic data (see attached R script for estimation).


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HGF is the ligand for Met, which is a membrane receptor involved in multiple transduction pathways. Gene ID 4233 we're looking at a single gene product for MET. If we're just reading through the wikipedia page for c-Met, when HGF binds to Met, it activates the tyrosine kinase activity of Met. Met recruits Gab1, and this complex mediates interactions with ...


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Reiterating the above comments. Have a look at Tajima's D. It provides an estimate for the number of segregation sites for a population under a neutral mutation model. The general form of the estimation for a diploid population is $E[S]=4N\mu\sum_{i=0}^{n-1} \frac{1}{i}$. Here the mutation rate of is per-genome not per-site, so $\mu=L * 10^{-9}$ where $L$ ...


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The fraction of polymorphic sites that exist in a population is dependent on the biology of the organism. For instance, you would expect to find different rates of polymorphism in related plants that have different breeding systems, e.g. in Silene [1]. Past bottlenecks are also expected to decrease polymorphisms [2]. So, the answer to your question would ...



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