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LUCA was the LAST universal ancestor not the first. Naturally it competed with other extinct species. My reseach suggests that LUCA was resulted from the fusion of 2 genomes. The evidence for this is that on reconstructing the amino acid sequences for LUCA enzymes we find some contain no cystine but do contain tryptophan or the opposite.


I understand heterozygote inferiority (also underdominance or heterozygote disadvantage) as the opposite of heterozygote advantage, that is, lower fitness of the heterozygous genotype than either homozygote (as reference, see Hedrick, 2009, p. 119). I haven't seen the term structural underdominance before. However, heterozygote disadvantage can sometimes be ...

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