Hot answers tagged stem-cells
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Fetal RNA - mRNA and microRNA - has been detected in maternal blood as shown in this report. Here's a second report showing how fetus gives back to repair the maternal myocardium - fetal cells traffic to an injured maternal myocardium and undergo cardiac differentiation.
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The easiest answer to this question is NO. We will not be able to print humans any time soon, if ever. Despite the potential of the technology, it will likely still make more sense to use stem cells to fight genetic diseases, create limited cellular masses such as hearts and other organs, and to do reconstructive surgeries such as skeletal repairs.
The ...
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There are several competing models of metastasis, and this question does go right to the differences between them.
The primary thing to remember about CSCs is that all evidence suggests that they are a tiny, tiny subset of tumor cells.
CTCs, meanwhile, consist of whichever cells manage to acquire the right combination of motility, invasiveness, and ...
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Stem cells are not all 'unipotent' - they cannot necessarily differentiate into any type of cell. For instance, resident stem cells in tissues such as muscle - myo-satellite cells - are partially differentiated and during cell division one daughter differentiates further to become a myocyte (for example), and the other daughter the replacement myosatellite ...
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I heard that as well and was skeptical at first, but apparently there IS science to support it- http://mblogs.discovermagazine.com/80beats/2011/11/21/helpful-mouse-fetuses-naturally-send-stem-cells-to-mom-to-fix-her-damaged-heart/ Officially found with mice, but it supports how some women that suffered damages while pregnant are sometimes found with their ...
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No.
The reason is that development is extremely important for getting tissue organized on the appropriate scale. We can place groups of cells or a scaffold somewhere, but we can't assemble a working cell from component bits, much less make one that has one end in one's toe and the other in the spine (as is the case with sensory neurons for our legs).
So ...
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Autologous stem cell transplants are used to treat individuals who have had their bone marrow destroyed or damaged by diseases such as lymphomas or by irradiation or cancer treatments. As they are damaged and potentially cancerous, they are removed. They are then replaced in the transplant. The whole idea is to destroy all the cells before transplanting the ...
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Another paper from Yamanaka's group explains Fbx15.
It says:
Inactivation of Oct3/4 in ES cells led to rapid extinction of Fbx15 expression.
Fbx15-null ES cells were normal in morphology, proliferation, and differentiation. These data demonstrate that Fbx15 is a novel target of Oct3/4 but is dispensable for ES cell self-renewal, development, and ...
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I'm not sure about the first developmental stages but, given you already have hundreds of cells with slightly different physiology, the next developmental stages like dev. of neural tube happen through excretion of translation factors and growth factors in several cells. Each of those cells that are in a region where more than one excretion overlaps get a ...
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