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The quantity $r$ must be a frequence, measured in hours $^{-1}$. So it cannot be measured in bacteria/hour/cell. If the number of bacteria is multiplied by 4 each hour, this means that $\exp r= 4, $ or $r= \ln 4 $ , or 1, 39 per hours.


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Generally speaking, structure prediction programs look only at the thermodynamic minimum, without consideration of the kinetic trajectory of folding. The main reason for this is mostly time considerations. It's very difficult to accurately model the true folding pathway of even a moderately sized protein. With special tricks and a bunch of computing power, ...


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The issue of IBD and IBS can indeed be confusing. The identity by state definition refers to the fact that at some point two individuals, even if they are not related to each other, present the same allele at a specific locus. Because of their un-relatedness this similarity probably arose from a similar mutational event. On the other side, with IBD two ...


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I am a bit wobbly on the subject, but I think the most important bit of information is that they are re-parametrising Wright's (1951) hierarchical analysis of variation, "F-statistics," "hierarchical partitioning of variation," or "population parameters," depending on whom you ask. The parameters correspond as follows (on the bottom of p.1358): Fit=F, Fis=f, ...



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