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Whether a reaction is reversible or irreversible, in the presence or absence of an enzyme, is not related to activation energy. An enzyme lowers activation energy in both directions. A reaction is reversible or irreversible depending on the conditions in which this reaction occurs. If there's a sustained high concentration of substrates, most of the ...


In a coupled reaction energy required by 1 process is supplied by another process. For example: glucose + phosphate becomes glucose.6.phosphate. This is an endergonic reaction and the energy is supplied to this reaction by another reaction which has to be exergonic reaction i.e. ATP which can become ADP+energy.

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