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There is not very much transport of ions or water through the upper layer of the skin, mainly responsible for that is the stratum corneum (SC). Through this layer you will get only with small lipids and also substances which are able to penetrate the lipid layer of the cells like chloroform or DMSO. I think therefore that it is pretty unlikely that you can ...


Whether a drug can be delivered transdermally? I think that carriers can be formulated to carry a small molecule through the skin into circulation, so I don't even know about lipophilicity. I believe if you spend enough money, you can overcome many of these problems. I think that pharmacology might be just as important. I think the first condition of a ...

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