Tag Info

New answers tagged

1

Theoretically there are two very basic things to consider in judging virulence for the secretion systems: a) Can it secrete into any human cell? (If not, chances of being virulent are smaller, but not zero as whatever is secreted in the environment of a cell could also be harmful for the cell.) b) Does it secrete some agent (protein, RNA, molecule), which ...


1

I think you cannot find a better answer then the following review: http://www.nature.com/nrmicro/journal/v13/n6/full/nrmicro3456.html It was published in 2015, and it gives a good overview about the secretion systems. Anyway, T6SS can also be virulent. Vibrio cholerae can use an effector of this SS to cross-link actin in the host cell and modify its ...


2

Interactions denote protein-protein interactions, which means physical association between proteins. By nature, these networks/graphs are undirected. Replication interactions (actually a not very good term) denote gene regulatory interactions that affect HIV replication. These sets also include the regulatory effects of HIV genes on host genes (and hence ...



Top 50 recent answers are included