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5

Besides viral infections there are different pathways for cells to take up dsRNA. Inside the cells these dsRNA are processed by Dicer which processes these RNAs into small interfering RNA, which play an important role in the regulation of gene activity. These pathways have mostly been researched in Drosophila and C. elegans, I am indicating where evidence ...


0

As it stands this question may be to broad since there are many different ways of introducing exogenous DNA into cells. I'll give a few examples. You mentioned the viral method, which is called transduction in prokaryotes. Introducing exogenous DNA by non-viral means is generally called transformation in prokaryotes and transfection in eukaryotes. There ...


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I found this safety sheet in the topic. SECTION IV – STABILITY AND VIABILITY DRUG SUSCEPTIBILITY: Unknown. S-adenosylhomocysteine hydrolase inhibitors have been found to have complete mortality protection in mice infected with a lethal dose of Ebola virus (30). DRUG RESISTANCE: There are no known antiviral treatments available for human ...


1

It is not airborne, because if it had be we would have a really big problem. Normal immunocompetent mice are not susceptible to non-adapted filoviruses. There are therefore two strategies available to establish a murine model of filovirus infection: adaptation of the virus to the host or the use of genetically modified mice that are susceptible to ...


15

Interesting question and hard to answer definitively. First of all: It seems still pretty clear that the major (and by far most important) infection route comes from direct contact with infected people or their body fluids and that aerosol transmission is of far less significance. Ebola is infecting cells of the immune system (mostly macrophages and ...


0

I think the disadvantages are mostly economical in that region and so they has nothing to do with epidemiology. Possibly a long term effect can be, that the economy of the region turns from bad to worse, which can affect the healthcare too, but that's just speculation. The advantages are obvious, ebola is quarantined at some level, so these measures prevent ...


12

This really depends on the environment, one study (listed below as reference 1) found that the Ebola virus can survive under ideal conditions on flat surfaces in the dark for up to six days - see the figure from the same publication. However, the virus is quite sensitive to UV radiation (see reference 2 for all the details) and most viral particles are ...


5

This is now how new viral diseases are being named, possibly because one can have/carry a virus without having a disease (e.g. HIV, herpes simplex, etc.). It is not as uncommon as you think. A bit of googling will turn up reputable sites which discuss the epidemiology of Hantavirus disease, Hendra Virus Disease, Powassan Virus Disease, Lake Victoria ...


4

First, I want to note that ddiez has a good answer, but I thought this was good question to have a more expanded answer on immunology and pathogenesis. The First thing we need to establish what is a "cold". The most common cold is rhinovirus (HRV), but the second place holder is a little harder to define. For example, respiratory syncytial virus (RSV) ...



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