Unanswered Questions

16
votes
1answer
631 views

Additive genetic variance components from LMER in R

I've set up some dummy data in R which makes 40 genetically related lines, they are all siblings within a line so are genetically related by a factor of ½ thus additive genetic variance should be ...
11
votes
0answers
173 views

What is the percentage of people living in England in 1500 AD whose lineage is still alive?

This sounds a bit random but it stems from a lecture in statistical genetics which I attended a while ago. We were shown a population lineage graph from which it was clear that most lineages go ...
11
votes
0answers
89 views

What have the L-systems (Lindenmayer systems) been actually used for in biology?

Wikipedia: An L-system or Lindenmayer system is a parallel rewriting system and a type of formal grammar. L-systems were introduced and developed in 1968 by Aristid Lindenmayer, a Hungarian ...
10
votes
1answer
106 views

How do burrowing animals get enough oxygen?

Tree borers make a small hole in a tree. At the end of it, they chew on wood to elongate the tunnel. They digest food and grow. All this takes oxygen. The entrance to the tunnel is generally small. ...
10
votes
1answer
98 views

Unilateral damage to vagus nerve

Context: The vagus nerves supply the neck viscera, heart, lungs and gastrointestinal tract. They join around the oesophagus to form the oesophageal plexus. Question: Would damage to one vagus nerve ...
9
votes
1answer
200 views

Why do crabs spit?

Last year I photographed this juvenile Sally Lightfoot Crab (Grapsus grapsus) 'spitting' (click for larger view): I thought I'd look up more information on this behavior, but couldn't find any ...
8
votes
0answers
98 views

Understanding the brain: how are neurotransmitters released in the brain?

I have a basic knowledge of how neural networks work. A potential difference is created that forces sodium, potassium, chloride, and calcium ions to flow which carries an electrical signal to the end ...
8
votes
0answers
145 views

Why do bananas go brown quicker in the fridge?

Perhaps the title should be: Why do specifically bananas go brown quickly when left in the fridge? Bananas go brown over time because of the oxidation of phenol residues. Bananas go brown quicker ...
8
votes
0answers
103 views

Selection for less efficient egg transfer in Human Botfly life cycle

I have heard that the Human Botfly transfers its eggs through other invertebrates [1], and it strikes my curiosity that if an insect could simply land on its host directly to deposit its eggs, then ...
8
votes
0answers
93 views

How to define “Quasifixation” in continuous approximation of finite population?

Background Many models including the famous very first models derived by Sir Ronald Fisher in his early career, assume infinite population size. In an infinite population, an allele can rise in ...
8
votes
0answers
147 views

At which step apply a detection filter when preprocessing microarray data? (Before/After normalization, batch effects removal)

I am trying to understand what is the best practice when preprocessing microarray data using a detection filter (on scanner p-value). Suppose I have a microarray dataset that I have to normalize with ...
8
votes
2answers
96 views

Why aren't plants' roots as diverse as leaves?

I have been doing some gardening recently and I suddenly realised that all plants have superficially identical non-woody roots of the same size from gigantic trees to small fruiting plants and ...
7
votes
0answers
59 views

Standard practice for generating rarefaction curves from Next Generation Sequencing data

We have a few million 18S reads from a particular environment. The reads have been clustered into Operational Taxonomic Unit (OTU), and the OTUs annotated against a reference database. To generate a ...
7
votes
3answers
85 views

Following DNA replication during S-phase of the cell-cycle, are all genomic regions subjected to the same stringent level of DNA-Repair?

To my (limited) understanding, there are 2 main ways that mutations can occur in DNA: Environmental (UV, etc) and mistakes during cell division. I was wondering if there is a mechanism that can give ...
7
votes
0answers
231 views

Contact Inhibition of Cell Division: Signaling Pathway

The following article refers to contact inhibition of cell division in epithelial cells, specifically MDCK cells: Collective and single cell behavior in epithelial contact inhibition. In their review ...

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