Unanswered Questions

7
votes
0answers
92 views

effect of pupil responses on the electroretinogram

The electroretinogram is generally considered to reflect the retinal processing of a light stimulus, typically a photoreceptor response followed by secondary neuronal activity. However, I am wondering ...
7
votes
0answers
195 views

Additive genetic variance components from LMER in R

I've set up some dummy data in R which makes 40 genetically related lines, they are all siblings within a line so are genetically related by a factor of ½ thus additive genetic variance should be ...
7
votes
0answers
144 views

How does Sodium Valproate cause neural plasticity

I have been reading a fascinating paper: Valproate reopens critical-period learning of absolute pitch 18 individuals were given Sodium Valproate (VPA) for a fortnight during which they trained on a ...
6
votes
0answers
49 views

How to define “Quasifixation” in continuous approximation of finite population?

Background Many models including the famous very first models derived by Sir Ronald Fisher in his early career, assume infinite population size. In an infinite population, an allele can rise in ...
5
votes
0answers
107 views

What is this fuzzy, black fungus that grew on my plates in the 4⁰C room?

I often find the fungus below growing on my (ostensibly) sterile plates in the 4⁰C room. Presumably it takes a few days to reach this size. The colony looks puffy and dimpled in the middle, like a ...
5
votes
1answer
71 views

Intuitive explanation for Kin- and Group- selection

It is known from theoretician in the field of kin selection that kin selection (inclusive fitness theory) and group selection are actually two sides of the same coin. In other words, these two ...
5
votes
0answers
185 views

Cytoplasmic determinants - protostomes and deuterostomes

Cytoplasmic determinants are spread unevenly in the egg, and so when embryo starts forming (cells start dividing), the determinants are also unequally divided between cell. This unequal distribution ...
5
votes
0answers
285 views

Reason for seeing grid-like patterns when strobing a solid black-white image?

I was trying to do some stimulation for SSVEPs by strobing a solid black square and a solid white square. Weird thing was, I ended up seeing weird grid like patterns that looked like this, always of ...
5
votes
1answer
94 views

What controls leaf senescence in deciduous tree species, and how can I predict it?

If I want to predict litterfall, what data do I need to collect, and what statistical model might I use? For example, I might use the following coding to record phenological stage every other day, or ...
5
votes
0answers
104 views

Do mammals develop tolerance to anticholinergics?

I know that first generation H1 antagonists, commonly known as antihistamines have anticholinergic effects. Their sedative side effects go away due to tolerance, but as for their anticholinergic side ...
5
votes
0answers
127 views

What temperature should mammalian B-Cells be stored at outside of the incubator?

I'm working with murine B-cells. The general protocol is to keep cells on ice to keep them from dying but I've noticed that it makes these cells aggregate and precipitate out. I've heard suggestions ...
4
votes
0answers
29 views

Grapefruits and CYP3A4

Grapefruit juice contains furanocoumarins, which irreversibly inhibit CYP3A4. For this reason, when one is taking certain medications it is necessary to not eat grapefruits because the inhibition of ...
4
votes
0answers
37 views

What are parental antagonism & parental conflict?

I've been reading the chapter by Haig et al in The Genetics and Biology of Sexual Conflict. I think this chapter has them quite unclearly defined. Could anyone describe these two phenomenon more ...
4
votes
0answers
27 views

Mechanisms of Gene*sex / Genotype*sex interactions

I'm looking for suggestions of the mechanistic level at which genotype/gene * sex interactions can occur. These give different phenotypes from the same geneotype dependent on the sex they are ...
4
votes
0answers
13 views

Would constant light or fading light be registered as more wakefulness promoting by the Supra Chiasmatic Nucleus?

During the fall and winter season, a number of people are experiencing Seasonal Affective Disorder. One of the way it has traditionally been treated is with a dedicated lightbox - a very high ...

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