Unanswered Questions

9
votes
0answers
119 views

Effect of pupil responses on the electroretinogram

The electroretinogram (ERG) is generally considered to reflect the retinal processing of a light stimulus, typically a photoreceptor response followed by secondary neuronal activity. I am wondering ...
7
votes
0answers
231 views

Additive genetic variance components from LMER in R

I've set up some dummy data in R which makes 40 genetically related lines, they are all siblings within a line so are genetically related by a factor of ½ thus additive genetic variance should be ...
7
votes
0answers
161 views

How does Sodium Valproate cause neural plasticity

I have been reading a fascinating paper: Valproate reopens critical-period learning of absolute pitch 18 individuals were given Sodium Valproate (VPA) for a fortnight during which they trained on a ...
6
votes
0answers
25 views

Why can good music raise goosebumps?

Listening to really good music right now, I was wondering why it raises goosebumps. Is there any physiological reason for this reaction to specific wavelengths or something? EDIT: Due sometimes ...
6
votes
0answers
60 views

How to define “Quasifixation” in continuous approximation of finite population?

Background Many models including the famous very first models derived by Sir Ronald Fisher in his early career, assume infinite population size. In an infinite population, an allele can rise in ...
5
votes
0answers
48 views

Non-harmful bacterial invasion of cells

There are bacteria that can enter body cells as parasites. Could it be that some of these are benign, such that the guest will not kill the host cell it lives in (in human)?
5
votes
0answers
83 views

Circular mRNA to produce long proteins

Ribosomes can read mRNA and produce proteins, if we somehow make a circular mRNA for the ribosome to bind onto, it will make infinitely long "proteins", (since ribosomes can make very big proteins, I ...
5
votes
0answers
207 views

Cytoplasmic determinants - protostomes and deuterostomes

Cytoplasmic determinants are spread unevenly in the egg, and so when embryo starts forming (cells start dividing), the determinants are also unequally divided between cell. This unequal distribution ...
5
votes
0answers
299 views

Reason for seeing grid-like patterns when strobing a solid black-white image?

I was trying to do some stimulation for SSVEPs by strobing a solid black square and a solid white square. Weird thing was, I ended up seeing weird grid like patterns that looked like this, always of ...
5
votes
0answers
107 views

Do mammals develop tolerance to anticholinergics?

I know that first generation H1 antagonists, commonly known as antihistamines have anticholinergic effects. Their sedative side effects go away due to tolerance, but as for their anticholinergic side ...
4
votes
0answers
44 views

Is the six-layer cortex model of the mammalian cortex still the most accepted model?

I've been reading a bit about the different layers of the cerebral cortex and its clear that certainly not every region of the cortex has the same number of layers. Thus, the idea that every region ...
4
votes
0answers
36 views

What is the difference between organelle membranes?

Cells and organelles are contained in lipid bilayers. I'm particularly interested in eukaryotic organelle bilayers and the biophysicochemical differences between them. Many papers assume a ...
4
votes
0answers
38 views

Do people that don't feel pain shiver in the cold?

There are a few diseases that cause an insensitivity to pain. This question asks about the relationship between the cold and pain, which got me thinking: Is shivering a response driven by the ...
4
votes
1answer
83 views

Grapefruits and CYP3A4

Grapefruit juice contains furanocoumarins, which irreversibly inhibit CYP3A4. For this reason, when one is taking certain medications it is necessary to not eat grapefruits because the inhibition of ...
4
votes
0answers
43 views

What are parental antagonism & parental conflict?

I've been reading the chapter by Haig et al in The Genetics and Biology of Sexual Conflict. I think this chapter has them quite unclearly defined. Could anyone describe these two phenomenon more ...

15 30 50 per page