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bio website mckuhn.de
location Dresden, Germany
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visits member for 1 year, 5 months
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May
8
comment Are there more descriptive ways of naming genes and gene interactions?
@AlexStone: there are pathways that can be given a nice name, e.g. genome.jp/kegg/pathway.html -- but even then there will be more functions to the pathway than what can be encapsulated in the name
May
2
comment Do marine deep sea life forms exhibit circadian rhythms? If so, what entrains them?
very interesting question. just a pointer: en.wikipedia.org/wiki/… plankton migrates between 100 and 1000 meters of depth, so there are regular signals communicated downwards
Apr
16
comment Software for counting fly eggs
here's another image analysis package that may do what you want fiji.sc/Fiji
Apr
8
comment Confusion related to a term probe-by-background interaction
cross-posted with BioStar: biostars.org/p/68510
Mar
8
comment Combining gene expression data from two species
Sometimes you have a strain-specific gene duplication, which you probably want to exclude to keep things simple. So you can check for each species if there's more than one gene associated with an ODB6_OG_ID, and remove those.
Feb
27
comment Specific enzyme for C. elegans
what is your actual question?
Feb
26
comment What is benjamini
please don't cross-post with BioStars without acknowledging it in your question -- biostars.org/p/64888
Feb
19
comment What are some alternatives to Charles Darwin evolution except creationism?
So you're asking for alternatives to "species evolve/change during time"? Then they must be unchanging, created ex nihilo.
Feb
19
comment What are some alternatives to Charles Darwin evolution except creationism?
What do you mean by "Charles Darwin evolution"? We certainly know much more than Darwin did in his day, see en.wikipedia.org/wiki/History_of_evolutionary_thought
Feb
7
comment What is the mechanism behind ventilatory acclimatization?
not a complete answer, just a comment: $CO_2 + H_2O$ <--> $H_2CO_3$. This is going on all the time (e.g. in a soda bottle) without the need for an enzyme.
Jan
23
comment Is copy number variation dynamic?
the answer to this question depends on the scale you're looking at: individual cells? tissues? organisms? tumors?
Nov
29
comment What is a good list of unsolved protein structures?
You can also filter for different protein model databases like "ProteinModelPortal" to get rid of proteins that can be modelled based on homology.
Nov
22
comment How can I compare rates of evolution for two sets of proteins?
@terdon: if you want to compute ka/ks ratios, you need to look at the nucleotide sequences, no?
Nov
22
comment How can I compare rates of evolution for two sets of proteins?
The eggNOG database also contains alignments for protein families, but these are on the amino acid level. So you would still somehow have to go back to a nucleotide alignment, which I'm not quite sure how to do. :-/ Might be a good question to ask on BioStar with its larger bioinf audience.
Nov
22
comment How can I compare rates of evolution for two sets of proteins?
are you working on species that have already been sequenced (for which you might info in databases), or do you have novel sequencing data?
Nov
20
comment Why do living organisms replicate itself or procreate
Yes, reproduction is part of the definition of life. However, this doesn't mean that a sterile animal doesn't live.
Nov
20
comment Multiple sequence alignment - how to align everything to 1 gene sequence?
Which kind of result do you want to have? One alignment with three sequences, or two pair-wise alignments? If the former, what would you do if one of the 1000bp sequences causes a gap in the reference sequence?
Oct
19
comment What is the difference between orthologs, paralogs and homologs?
Another pet peeve: homology is qualitative, not quantitative. So saying "significant homology" or "weak homology" is just wrong.
Oct
17
comment Is Homo sapiens the only species capable of prioritization?
Good point! too bad the other members of our genus are extinct.
Oct
3
comment Are there any substance that are more dangerous at low dose than at higher dose?
I agree, but my answer is true to his original question