4,870 reputation
1435
bio website nicolaromano.net
location Montpellier, France
age 33
visits member for 2 years, 4 months
seen 2 days ago

I'm a researcher in neuroendocrinology

I'm interested in all that regards pattern recognition, time series analysis, rhythms etc.

My current research focuses in the exploration and modulation of the neuro-endocrine patterns that contribute to the generation of hormone pulsatility.


Mar
31
comment Cells created using differently aligned proteins
I don't see why. If everything in nature was specular, well, it could in theory work very well! I think we simply do not have any proof in favour or against to say more...
Mar
31
comment Cells created using differently aligned proteins
This assumes lots of things. There may be instances in which the active site is a bit "loose" to allow for multiple substrates and in which a D-aminoacid would not harm too much. Plus if everything, including the substrate, was D-form I bet there would be a high chance of it working. There are examples of antibiotics becoming more specific or selective when one aminoacid is changed from L to D (e.g. this and this)
Mar
31
comment Nervous system : Nerve signals
Would you have any references for the wrong innervation?
Mar
31
comment Brainbow fluorescence labeling technique
I would suggest to also read the original Brainbow paper by Livet and colleagues, which goes in details in the genetics of the system and its variations. Transgenic strategies for combinatorial expression of fluorescent proteins in the nervous system - Livet et al., Nature 2007
Mar
30
comment In Japan, mean human body is 36.0 °C, why so different from Europe?
Do you have any references for that (temperature in various parts of the body and methods of measuring in different countries)? It would be quite important to cite them in this case...
Mar
30
revised Substitute 25mM dNTPs mix with 10mM dNTPs
formatting formulas, spelling, general formatting
Mar
30
revised Influence of alcohol on brain cells
equation and links formatting
Mar
29
awarded  Enlightened
Mar
29
awarded  Nice Answer
Mar
29
comment Cells created using differently aligned proteins
That seems extremely far fetched to do with current technology... in any case, natural aminoacids are called L-aminoacids and their "mirror counterparts" are the D-aminoacids. Maybe that can help with your search?
Mar
29
revised Is half-a-tablet of X a substitute for a tablet of X/2?
added 655 characters in body
Mar
29
answered Is half-a-tablet of X a substitute for a tablet of X/2?
Mar
21
comment How do cellphones calculate heart rate?
@WYSIWYG: if you look at ~1:40 of the the Siggraph 2012 video you will see that the algorithm works for dark skin tones too.
Mar
21
comment If everybody DNA is different then how blood can match even with matching blood group?
Since the antigens are genetically encoded DNA IS the determining factor when it comes to a blood transfusion. Just not all of it.
Mar
17
comment How does DNA mess up
Transitions are transformations between purines or between pyrimidines (that is C becoming a T or viceversa and A becoming a G or viceversa). Transversions are between a purine and a pirimidine (the red arrows in the picture). You can also have so called "wobble pairings" or "non Watson-Crick pairings" such as C-C, T-G, A-C.
Mar
17
answered How does DNA mess up
Mar
16
comment Conserved proteins are non immunogenic
@biogirl: most commercial antibodies are generated by injecting the antigen into an animal. Most used speciars are rabbits, sheep, goats, chicken, guinea pigs, rats and mice. You can get antibodies synthesized in bacteria as Chris pointed out, but I would say that is not the most common way nowadays.
Mar
16
comment If DNA has a half life of about 500 years, how can old seeds be planted?
+1 for showing that the Materials and Methods section of an article is as important (if not more) than its Results section.
Mar
16
revised If DNA has a half life of about 500 years, how can old seeds be planted?
formatted links and math, capitalised DNA
Mar
16
answered Conserved proteins are non immunogenic