5,574 reputation
1538
bio website nicolaromano.net
location Edinburgh, United Kingdom
age 34
visits member for 3 years
seen Nov 19 at 15:30

I'm a researcher in neuroendocrinology

I'm interested in all that regards pattern recognition, time series analysis, rhythms etc.

My current research focuses in the exploration and modulation of the neuro-endocrine patterns that contribute to the generation of hormone pulsatility.


Oct
20
answered Why are things conscious?
Oct
20
comment Why are things conscious?
Could you please link to some literature at this regard? I never heard about "cell irritability" in the context of the nervous system, or when speaking of multicellular species for that matters. I think that for the scope of this site a proper neuroscience answer would have to be preferred to a phylosophical answer (Leibniz is all nice and good, but he was not what I would call a neuroscientist).
Oct
19
comment Is there any advantage to one blood type over another?
Can you provide references to the original research showing that? I cannot really find any on Pubmed. What I found is that individuals of Duffy- blood group are resistent to Plasmodium vivax invasion (Langhi and Bordin, Hematology 2006), but I cannot find anything on AB0. Also see: ncbi.nlm.nih.gov/books/NBK2271
Oct
19
comment Unexplained pain in the legs at night, possibly due to peripheral nerves - diagnosis and cure?
Questions requesting medical advice are off-topic here
Oct
16
comment Why do I have a lot in common with my mother?
All of the other comments are sure true, but you should also consider confirmation bias. You have been reunited with someone after a long time and probably the things you have in common surprise you more than those that you have not in common (which you tend to forget). You should ask someone else (best would be a stranger) to take, say, 50 different "characteristics" (e.g. "like cinnamon in cake", "like skying" etc.), then count how many you have in common with your mother. Then repeat the same exact count with someone who is unrelated to you.
Oct
13
comment What to do with a DNA sequencer?
Also, will there be some money available for the project, and if so how much? That may be a limiting factor for certain experiments.
Oct
11
comment Would it be correct to state that any biological difference between the sexes has to be found in the Y chromosome?
There are two main flaws in your reasoning: 1) you are assuming that male autosomes are equal to female autosomes, which is not necessarily true and 2) you are assuming that such complex traits are monogenic which is definitely false
Oct
10
comment Why do different bacteria have different shapes?
@fileunderwater: I see it as a very interesting biological question. I would rather compare it to "why do birds have differently shaped beaks?"
Oct
6
comment Does our DNA change during our lives?
+1, however it is to note that stress (depending on the definition of stress that you want to use, some are rather large) is not the only stimulus that can generate epigenetic changes. For instance maternal behaviour is well known for having epigenetic effects (e.g. ncbi.nlm.nih.gov/pubmed/15220929). Surely, you may say that at the end it is stress-related, as you modulate GR, but it is not directly caused by stress (again, you should define stress more clearly so we know we're talking about the same thing).
Oct
5
comment Does our DNA change during our lives?
I see the question as much more general. "Does DNA change during our lives?". The answer is yes. Schizofrenia is meant to be just as an example...
Oct
4
comment Does our DNA change during our lives?
sorry, but how can you say that it is impossible for a drug to affect a foetus so that it becomes schizophrenic? I can see many biologically plausible mechanism for that. Your answer is misleading because you are saying that the effect of the drug "can absolutely under no conditions be passed on to your child". Which is not necessarily true.
Oct
4
comment Does our DNA change during our lives?
@terdon: I doubt there is a specific change for "piano playing ability", but I would not be that surprised whether there were changes to, say, genes involved in neurotransmission in cognitive areas of the brain. As for whether epigenetics changes are or not changes to DNA... well definitely methylation of DNA is a change to the DNA, that is really not debatable. I guess that strictly speaking histone modification are modifications of chromatin and not DNA, but that's nitpicking...
Oct
4
comment Does our DNA change during our lives?
@terdon: see my comments to vonMises's answer. Epigenetic changes to the genome happen because of environmental changes, mutation is not the only way to change genetic information.
Oct
4
comment Does our DNA change during our lives?
Mutation is random, and that is the only way DNA can change.. This is not true. Mutation is not necessarily random, mutagens may be more or less selective. Also, again, mutation is not the only way DNA can change, there are plenty of epigenetic changes that can play a big role in shaping behaviours. Just as an example, you may want to have a look at this paper: ncbi.nlm.nih.gov/pubmed/22941276
Oct
4
comment Does our DNA change during our lives?
A person who becomes schizophrenic because of drug use does not become any more prone to having schizophrenic kids than a person who doesnt do drugs. This is not that obvious. First, if drugs are taken during pregnancy/nursing they may as well influence the child. Second it is now well known that many drug can produce epigenetic modifications that, in certain situations, can be transmitted transgenerationally.
Oct
1
comment How do rodenticides with delayed effect work?
Not sure about the specifics of rodenticides but you should take into consideration that a drug may not be directly bioavailable. It may be given as an inactive form which is metabolized to the active form. It may be retained in adipose tissue and slowly released. Also, the effect which may be fairly rapid, but not immediately fatal. If I remember correctly rodenticides are often anticoaugulants, so the effect may not be immediatly obvious.
Oct
1
comment Is evolution true as Darwin said?
You may want to look at the excellent series of links reported here: skeptics.stackexchange.com/questions/2057/…
Sep
29
comment What non invasive methods of estimating Body Time are there?
Don't forget cortisol/corticosterone!
Sep
28
comment Deducing synaptic strength from electron micrographs?
@WYSIWYG: I would be extremely wary of using such approach... you should really combine it with some ephys.
Sep
27
comment Changing the definition of life?
well, I do not know many people who think genes are alive...