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May
7
awarded  Popular Question
May
6
comment How does frame-shift mutation not absolutely ruin the organism?
@canadianer you're absolutely right, of course. I have no idea what I was thinking of. I leave genomics for 5 years and I forget the basics! Answer edited, thanks for pointing it out and my apologies for being dense.
May
6
revised How does frame-shift mutation not absolutely ruin the organism?
removed stupidity
May
6
comment How does frame-shift mutation not absolutely ruin the organism?
@canadianer no, it will only affect the downstream sequence of its own exon. The splicing signals are not codons and won't be affected unless the frameshift occurs in the acceptor or donor sequences themselves. How would a frameshift affect a different exon otherwise? Remember that we're discussing frameshifts that happen at the DNA level. Naturally, post transcriptional modifications/mutations are a whole different ballgame.
May
6
answered How does frame-shift mutation not absolutely ruin the organism?
May
5
reviewed Leave Open Oscillatory electrical system using a chain of neurons
May
5
comment Determining the percentage of the query of an alignment from a BLAST output
Please don't post images of text. Instead, use the formatting tools and add the text directly into your question. That way, we can copy it and test our answers. Also, since this is essentially a scripting question, please clarify what operating system you are using so we know what type of answer to provide. I assume you realize that your output shows that residues 4 through 146 of a 146aa query are aligned, right?
May
2
revised Identify chromosome location from gene nucleotide or amino acid number
deleted 2 characters in body
May
2
comment One Gene and many proteins
This question cannot be answered in its current form. How many of the exons contain a valid START codon? How many exons are in UTRs? How many actually code for protein and don't contain in-frame STOP codons? Please edit and make it more specific.
May
2
revised One Gene and many proteins
Fixed English
May
2
revised During the process of correcting mutations via gene therapy, is the defective gene removed?
Fixed formatting. Please don't use code blocks for non-code. For one thing, it makes you have to scroll to read the whole line.
Apr
28
reviewed Leave Closed Why do people in the scientific community use terminology such as renal, hepatic, cardiac instead of kidney, liver and heart?
Apr
28
reviewed Reopen Why do fingers swell during cold winters?
Apr
28
reviewed Leave Open Neuroscience of mathematicians
Apr
28
reviewed Edit Measuring a plant's electric activity any instructions where to place electrodes?
Apr
28
revised Measuring a plant's electric activity any instructions where to place electrodes?
Formatting and spelling
Apr
28
reviewed Leave Open Oscillatory electrical system using a chain of neurons
Apr
28
reviewed Close Why can we control our breath rate but not our heart rate?
Apr
27
reviewed Close Our muscles give us the ability to move our arms but…?
Apr
27
reviewed Leave Open What causes the line patterns in the palm of the hand?