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May
11
comment chimeric sequences
Yes, but you're contradicting yourself. Some chimeric sequences are very real and exist in vivo. Others are artifacts, mistakes introduced by the sequencing process. Which ones are you asking about?
May
11
revised What is the difference between orthologs, paralogs and homologs?
edited body
May
10
comment Is there a possibility that medicine will affect the efficiency of natural selection?
You might be interested in this Q&A: How is evolution possible in contemporary humans?
May
10
comment Is there a possibility that medicine will affect the efficiency of natural selection?
"Humans aren't under a lot of selective pressure on a large scale right now." : That is completely wrong. Of course we're under selection! We live in a specific ecosystem and changes to that system affect our survival. We are under strong selective pressure to be animals that can survive a specific range of temperature, acidity and oxygen concentrations to name just a few. Anyway, the main driver of selection is always the way that mates are chosen and that is still going strong today. Not everyone in a generation reproduces => selection. Disease is a relatively minor player in this.
May
9
revised Evolution and the levels of selection
deleted 1 character in body
May
8
comment What does chromosome CHR_Un, CHR_MT in the ftp site of NCBI mean?
@dexterdev I did not answer this, Chris did. I just edited which is why you see my name there. I don't know what Chris meant by that since I can't find that file on the FTP site nor see it mentioned in the FTP's README (which, by the way, you should read).
May
7
revised What does chromosome CHR_Un, CHR_MT in the ftp site of NCBI mean?
Made the formatting homogeneous.
May
6
comment translation of scientific names
This question appears to be off-topic because it is about nomenclature and the meanings of words in dead languages, not biology.
May
6
comment translation of scientific names
All you need to do is use a Latin/English and/or Greek/English dictionary. This is not really related to biology but linguistics.
May
5
comment Genome Project Focusing on gene ADRB2?
I ask again, please clarify. Arg/Arg16 is not a gene, its a genotype; I think the gene you mean is ADRB2. You still have not told us what is missing from the tools you are using. You have not explained what exactly you want to visualize nor what exactly you are looking at. I am beginning to guess you are after SNP variations but I'm not sure. You mention vertebrates, does that mean you want to do a comparative analysis of some sort? Please edit and be more specific.
May
4
comment Genome Project Focusing on gene ADRB2?
@Masi, all of them do that, that's the point og a genome browser. Can you please edit your question and narrow it down? I still don't know what you need that neither the UCSC nor Ensembl offer you. The only way to choose between them is personal choice or specific tools provided but since you don't explain what you want to do, it's hard to help.
May
4
comment Genome Project Focusing on gene ADRB2?
I don't understand what you're asking. Ensembl has subsections that let you look at a single genomes. The fact that the database has other genomes is irrelevant. What are you calling the "original Human Genome Project"? Do you mean UCSC? What kind of data do you want to visualize?
May
4
revised Genome Project Focusing on gene ADRB2?
added 2 characters in body
May
4
comment Whole genome amino acid composition tool?
@Masi could you clarify how you would like the answer to be improved? Perhaps edit the question to define a specific statistical calculation you would like to see?
Apr
28
comment Modern alternatives of DNA footprinting
@canadianer ah! DNAse footprinting, OK.
Apr
28
comment Modern alternatives of DNA footprinting
Identify it as what? Guess the species of origin? Guess the individual it came from? Guess its function?
Apr
28
comment PDB file for Osteopontin (SPP1)
Is the structure known?
Apr
26
comment Sequence alignment scoring
@daniel the -4 in your score is because a T in seq1 aligned to a - in seq2 has a score of -4 in the table. The -1 is because TT has a score of -1 in the table. However, while I have actually worked with this kind of thing, I have never worked with it in depth and it was a few years ago now, I may well be wrong.
Apr
26
comment Sequence alignment scoring
@daniel in which case it is probably mistaken (my approach, not your text). Taking what you show out of context, I am simply using the score for each position. So, since T- has a score of -10 in your table, I am using that.
Apr
26
answered Sequence alignment scoring