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Apr
26
answered Sequence alignment scoring
Apr
26
comment Sequence alignment scoring
Could you explain how you get that -17? A gap costs between -2 and -10 depending on which one in the table in the OP. The score of the mismatch also changes. Where are your numbers coming from?
Apr
26
revised Sequence alignment scoring
edited tags
Apr
26
comment chimeric sequences
Do you mean chimeric sequences that are artifacts of the sequencing process or actual bona fide chimeric transcripts that are present in vivo?
Apr
25
comment psychological database with sequenced DNA records
I would be very surprised if such a thing exists. Apart from the privacy issues (OK, you can anonymize the data), there aren't to my knowledge any projects for such large scale sequencing of human samples. The closest I can think of is the 1000 genomes project but I doubt any psychological data will be included.
Apr
23
comment How to determine whether the energy of a stem-loop fold is significant or not?
A predicted stem loop of what? A nucleotide chain presumably, and most likely RNA but you need to tell us.
Apr
21
comment is there a way to do batch download for all gene pathways?
What pathways? From which database? What species?
Apr
16
comment Percentage of understood human DNA
You would need to define "understanding". This is not a book where we simply have to read the words. Each "word" can have multiple different functions and we can't say with complete certainty that we understand any of them 100%. We have a pretty good idea about a relatively large part of it but understand is a loaded word.
Apr
16
comment What is the main challenge in creating a chemical male contraceptive?
@shigeta neither men nor women have any desire to take chemical contraceptives. I don't see why that would be truer for men than for women. The only difference is that women are expected to while men aren't.
Apr
14
revised Which was the last significant event in human evolution? What's next?
Fixed minor errors
Apr
14
comment What exactly makes bananas go brown?
Ah OK, thanks. I thought you were suggesting that the oxidation of tyrosine molecules was responsible for the change of color.
Apr
13
comment What exactly makes bananas go brown?
Could you explain how tyrosine gets in there? What is it that's being oxidized? I assume you mean free tyrosine molecules and not those incorporated into protein right? If I'm missing something obvious, please point it out, biochemistry was never my strong point and I haven't worked in a wet lab since university.
Apr
13
comment Is it possible to have life in vacuum?
Define life. You can probably get viral spores that can survive and even some extremophile bacteria but in a dormant state. Would you consider something that is not interacting with its environment in any way at the moment alive?
Apr
13
reviewed Excellent Why do people use anti-inflammatory drugs?
Apr
13
reviewed Needs Improvement Electronic cigarettes (e-cigs), any health risks?
Apr
13
comment Electronic cigarettes (e-cigs), any health risks?
Please source your claims. You mention a risk of "nicotine intoxication". What's that? The nicotine high is precisely the reason why people smoke. Nicotine is not in itself particularly harmful, the dangers of smoking are primarily related to imperfect combustion and the subsequent production of CO and free radicals, not to the ingestion of nicotine as such. I have read pretty much everything published on the subject and have yet to see any evidence that e-cigs are harmful and have seen a lot of evidence that they are much safer than normal cigs.
Apr
13
reviewed Excellent In biosynthesis of cysteine and methionine, where does the sulfur come from?
Apr
13
reviewed Excellent Does antibacterial soap work chemically?
Apr
13
reviewed Satisfactory In the lysogenic cycle, does the provirus split from the cell's main genetic material for replication?
Apr
13
reviewed Needs Improvement Bioinformatics : Drawbacks of using ORA(Overlap Analysis)