2,871 reputation
525
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location Marseille, France
age 32
visits member for 9 months
seen 8 hours ago
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I am a computational biologist with a background in biology, not computers. My PhD work was on gene prediction and comparative genomics but my current research is in systems biology, specifically protein-protein interaction networks.


Nov
20
revised Interpreting SNP-in-gene associations from GWAS studies
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Nov
20
comment Multiple sequence alignment - how to align everything to 1 gene sequence?
Could you please clarify your question? The reverse strand of a sequence is not alignable to the forward strand. Also, i don't understand what you mean by complete gene, forward and reverse sequences. Do you mean the genomic sequence, the transcribed transcript and the reverse complement of that transcript?
Nov
17
comment Have there been any experiments that duplicate chromosome copies from 23*2 to 23*3 or 23*4?
I have tried to edit your question. I still can't understand what you are asking. Do you believe that simply increasing ploidity will boost life span?
Nov
17
revised Have there been any experiments that duplicate chromosome copies from 23*2 to 23*3 or 23*4?
I have tried to make your question clearer. Please check that i have not changed what you are trying to say.
Nov
16
comment Are genes associated with obesity selected for?
There are reasons beyond aesthetics why obesity is dangerous. Do not confuse obesity with "chubbiness", the latter can indeed be quite healthy and confer a selective advantage.
Nov
14
comment DAM enzyme distances move along the genome
I am not sure about this but I believe there is not minimum or maximum distance. Each Dam protein will cut and then disassociate from the DNA. I don't think it moves along while remaining connected. If this is correct (again, I am not sure, not my field) then there will be no min/max distance between restriction sites. It will just float around until it finds another DNA molecule and cut the first site it finds. This could be adjacent to the previous one or kilobases away.
Nov
14
revised DAM enzyme distances move along the genome
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Nov
14
reviewed Reviewed Is it better to take a half dose of paracetamol and a half dose of ibuprofen together rather than a full dose of either?
Nov
14
revised Is it better to take a half dose of paracetamol and a half dose of ibuprofen together rather than a full dose of either?
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Nov
13
reviewed Reviewed High Glucose vs Low Glucose DMEM for Cell Culture
Nov
13
comment Do effects of caffeine on human body change with habitual use?
While not an opioid, caffeine IS most certainly a drug (not sure what you mean by narcotic). It is also quite addictive as I can state from personal experience, but if that is no enough see, for example, here. In any case, it is certainly more addictive than many narcotics.
Nov
13
comment How is evolution possible in contemporary humans?
@yotiao, you're quite right of course. That's what I mean by "active selection is not the only mechanism of evolution" and it was also mentioned in DQdlM's answer below.
Nov
12
awarded  Necromancer
Nov
12
revised Is Homo sapiens the only species capable of prioritization?
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Nov
11
awarded  Revival
Nov
11
comment The probability of indirect human fertilization?
Strictly speaking of course, this is not an answer to the question but still, +1 :).
Nov
11
revised Which bacteria have the highest mutation rate?
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Nov
9
revised How is evolution possible in contemporary humans?
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Nov
8
comment Is there any biological reason for humans to rest after x days of work?
Don't forget, humans rest every day when sleeping. Whether you are at work or not, your body is still active, still "working".
Nov
8
revised what are the mechanics of sweating?
sorry, I'm a horrible pedant...