6,911 reputation
21347
bio website
location Marseille, France
age 34
visits member for 2 years, 3 months
seen 22 hours ago

Elected moderator on Unix & Linux. Feel free to @ping me in chat if there's anything I can help you with.

I am a computational biologist with a background in biology, not computers. My PhD work was on gene prediction and comparative genomics but my current research is in systems biology, specifically protein-protein interaction networks.

profile for terdon on Stack Exchange, a network of free, community-driven Q&A sites


Oct
14
reviewed Satisfactory Importance of knowing GC Content of an organism
Oct
14
reviewed Excellent Regarding the difference between cDNA library and RNA sequencing (Biochem. technique)
Oct
14
reviewed Satisfactory Why has grey hair evolved?
Oct
14
reviewed Satisfactory What is this vinca like vine?
Oct
14
reviewed Satisfactory What is the functional significance of the difference in cardiolipin/cholesterol ratio in different membranes?
Oct
14
reviewed Excellent Is there a biological mechanism for evolution encoded into our DNA?
Oct
10
revised Evolution, What would the first plants have been like?
Fixed typos
Oct
9
comment If DNA is the input, what is the output?
@canadianer well, you claimed "we actually do understand DNA" and I'd argue that we understand very, very little. Especially when it comes to complex questions like how "different outputs" are chosen (think alt. splicing/choice of splice site/cis+trans regulatory elements/% of genome transcribed/methylome and epigenetics in general etc, etc). We understand the basic mechanics but are still very very far from understanding the regulation.
Oct
9
comment If DNA is the input, what is the output?
You might find this article interesting: ncbi.nlm.nih.gov/pubmed/11504843.
Oct
9
comment If DNA is the input, what is the output?
@canadianer really? That's news to me. We understand a lot about it but not everything. Not even close to everything.
Oct
6
comment Open Source Variant Caller comparable to GATK Haplotype Caller?
You could also try asking on biostars.org.
Sep
30
awarded  Explainer
Sep
30
comment Is Sugar a stimulatant or a weak sedative?
Could you provide a summary of these arguments? It's better to have the answer here rather than on another site which is behind a paywall (not everyone has institutional subscriptions)
Sep
29
comment What is the difference between a fixed substitution and a single nucleotide polymorphism (SNP)?
I'd need more context to be sure but what makes you think that the substitutions were only a single nt? Also, that sentence could be read as having found 464 SNPs, of which 430 were fixed.
Sep
24
awarded  Autobiographer
Sep
24
comment Which C. elegans would be appropriate for general study?
What question do you want to answer? The "appropriate" decision will depend on what exactly you want to investigate. What conclusions will you want to draw from your research?
Sep
23
comment Does this “fleeing spiders leaving fields of webs” phenomenon have a name?
I doubt it will be called anything specific. It's just spiders fleeing a flood like any other animal.
Sep
22
revised Where do the electrons and protons formed from biological reactions go?
edited body
Sep
22
comment BLASTn vs ORF tools
@Raghavakrishna I'm sorry but I still don't understand. The details always depend on what you're actually doing. If BLAST gives you a hit, then that's a hit. Whether or not that is biologically relevant is another question and I can't answer that unless I know what question you are asking.
Sep
21
comment BLASTn vs ORF tools
@Raghavakrishna why would they be false positives because they align against the - strand?