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| bio | website | |
|---|---|---|
| location | Marseille, France | |
| age | 32 | |
| visits | member for | 9 months |
| seen | 7 hours ago | |
| stats | profile views | 25 |
I am a computational biologist with a background in biology, not computers. My PhD work was on gene prediction and comparative genomics but my current research is in systems biology, specifically protein-protein interaction networks.
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May 17 |
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Writing methods section on PCR amplication in a paper @kmm indeed it was not. |
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May 17 |
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Writing methods section on PCR amplication in a paper @AlanBoyd thanks! It's 22:00 here and I'm still in my lab writing a report for a grant I received, so my mind is not at its best. I knew that sec bothered me but I couldn't put my finger on it. WHile absolutely correct, your comment about min is nicely ironic given that what I read is: "@terdon or even better, use the correct abbreviation for seconds which is s, not sec(s). And use min for minutes (not mins) – Alan Boyd 4 mins ago". :) |
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May 16 |
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Are humans more aggressive during a full moon? Umm, what gives you that idea? Could you provide a reference? |
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May 16 |
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Why 20 amino acids instead of 64? There is no evidence of selenocysteine being "grafted" in. Much the opposite actually, it has even been suggested that "UGA was originally a codon for Sec in the anaerobic world, perhaps two to three billion years ago, and after introduction of oxygen into biosphere this highly oxidizable amino acid could be maintained only in anaerobic organisms or in aerobic systems which evolved special protective mechanisms". If anything it is cysteine that has been taking over. |
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May 14 |
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Why do ants dig surface paths? Well, that's the thing, It can't be flat, if it were there would be no wall or the wall would be higher than the surrounding area which is not the case. The overhang would be created naturally by the ants' walking down the path and does not imply that it was done on purpose. |
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May 14 |
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Why do ants dig surface paths? I mean I do not see any protection. Since there is no wall on the "southern" side, there must be a difference in altitude between the "north" and "south" areas pictured. If the ants were creating this path by walking down it, there would be walls on both sides. At best, perhaps the ants created the path just by walking down it, if there is a difference in altitude that is exactly what would result with no active effort from the part of the ants other than the act of walking. That is how paths are formed after all. |
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May 14 |
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Why do ants dig surface paths? How is that "protected"? It looks to me like there is a natural "cliff" which the ants are simply walking along. |
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May 14 |
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SNPs mapping into protein @MattDMo you've got a dirty mind... :) |
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May 13 |
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Does anyone know what marsupial this is? Why was this closed? Species identification questions seem to be on topic and this is no more localized than any other such question. @mad-scientist? |
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May 13 |
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What's the difference between shotgun sequencing and clone based sequencing? Umm, you realize that an answer to this will be quite a few pages long right? Why don't you look up some of the common sequencing technologies on wikipedia and post a more specific question? |
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May 8 |
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Why does blood come from mouth when people are shot in the chest area? Nice answer, +1. Could you include a link to where you got the image from please? |
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May 7 |
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Are there more descriptive ways of naming genes and gene interactions? You are absolutely right and gene names are often horrid. Just wanted to point out that one of the genes on your list is actually quite descriptive: FGF8 is fibroblast growth factor 8, doesn't get any better than that. |
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Apr 30 |
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How is gene expression estimated? @shigeta I know, I just have this graph from the conference I mentioned in my head (cannot find it) where the did a transcriptome level analysis and the correlation was pathetic. I'll find it somewhere it was a keystone meeting in Heidelberg can't be that hard to find. |
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Apr 30 |
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How is gene expression estimated? Wow, just found an article from 1998 stating that in yeast "We found that the correlation between mRNA and protein levels was insufficient to predict protein expression levels from quantitative mRNA data." And yet here we are, still using such data... |
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Apr 30 |
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How is gene expression estimated? Unfortunately I don't remember the details but I recently saw a talk in a conference where it was demonstrated that mRNA levels don't really correlate with protein levels. I mean, we've always kind of known this but the numbers shown were shocking (less than 50%, perhaps as low as 30). I will try and get a hold of a reference and post back. |
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Apr 29 |
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How is it possible for animated corpses to continue their activity? @shigeta wow, thanks for making me look that up :). Care to post a question and answer it with the basics of the tetrodotoxin and the zombification process? Wikipedia is not very informative on this. |
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Apr 27 |
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What percentage of protein isoforms have different functions? Yes, that is the problem in a nutshell. Most (all AFAIK) high throughput experiments tag genes, not proteins and assign function to the gene as opposed to a specific isoform. |
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Apr 27 |
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What percentage of protein isoforms have different functions? Thanks shigeta but I would not call proteins coded for by different genes isoforms (and neither does the wikipedia page you linked to, it talks about alleles of the same gene). They are paralogs or orthologs depending on their evolutionary history. I would only use isoforms to describe products of the same gene. I am also assuming that most isoforms have different functions, hence my question. I am looking for data to back that assumption up. |
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Apr 26 |
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Why dogs move their noses when smelling? What do you mean by "3:00 to 7:00 snorted"? |
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Apr 25 |
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Why dogs move their noses when smelling? Might just be mechanical, note that your nose also moves if you inhale strongly enough. |
