11,945 reputation
1920
bio website
location United Kingdom
age
visits member for 1 year, 7 months
seen yesterday

From the era before Sanger sequencing was invented.


2d
answered How is bacterial plasma membrane made?
Apr
13
revised Distribution of Physarum polycephalum tubes during starvation phase
deleted 2 characters in body; edited title
Apr
12
comment Why do three nucleotides code for one amino acid? Why not 5 nucleotides?
@Remi.b great! let's see what answers you get. In E coli it takes 40 min to replicate the genome, but they can grow with a doubling time < 20 min by reinitiating before the previous round of replication has ended. I was once told that the limit to growth is the exponential increase needed in ribosome number as more and more ribosomes are tied up just making ribosomes.
Apr
12
comment Why do three nucleotides code for one amino acid? Why not 5 nucleotides?
I'm always bemused by arguments based upon the metabolic cost of maintaining DNA. I estimate that for E. coli less than 0.06% of ATP is used in replicating DNA, so for a 4 base codon system this would rise but would still be well below 0.1 %. This doesn't strike me as the basis of a strong selective pressure.
Apr
12
comment Why do three nucleotides code for one amino acid? Why not 5 nucleotides?
Warning for the uninitiated - that table is not the 'standard code' , it is the mitochondrial code (AUA is Ile in the standard code).
Apr
12
revised Why do three nucleotides code for one amino acid? Why not 5 nucleotides?
added 21 characters in body
Apr
12
revised Troubleshooting for Agarose Gel Electrophoresis
deleted 1 characters in body
Apr
12
answered Are there any fungi that can digest humic acids?
Apr
10
comment Why are many anti-malaria drugs gap junction antagonists?
Could you give specific examples of antimalarials that block gap junctions? If they do, I'm pretty sure that this isn't anything to do with their antimalarial action. Most of the standard drugs interfere with the food vacuole of Plasmodium resulting in haem toxicity.
Apr
9
answered Why doesn't the sperm die if there is citric acid and acid phosphatases in the semen?
Apr
9
revised Why isn't the phosphoglycerate kinase reaction of the glycolysis pathway irreversible?
edited title
Apr
9
answered Why isn't the phosphoglycerate kinase reaction of the glycolysis pathway irreversible?
Apr
9
revised Why isn't the phosphoglycerate kinase reaction of the glycolysis pathway irreversible?
improved English, I hope
Apr
8
comment How do nutrients get to the cells they need to get to?
@max Basically, yes.
Apr
8
answered Possible Genotypes — Linked Genes
Apr
7
answered How do nutrients get to the cells they need to get to?
Apr
7
revised The effect of pH on enzymes
minor corrections
Apr
6
revised How was the Huntington's disease gene's location found?
edited title; added 1 characters in body
Apr
6
comment what is the effect of soda water on digestion?
do you have source for this observation?
Apr
6
revised What are mast cell membranes made out of?
added 23 characters in body