639 reputation
213
bio website lsauer.com
location Austria
age
visits member for 2 years, 1 month
seen Jul 23 at 6:57

Thanks to everyone who contributes to StackOverflow and StackExchange.


Profiles: about.me, @sauerlo , Google+, Snippets, Code, Writing, CodeProject


May
26
comment How do I view the simulated protein structure along with ligand in VMD?
->www.biostars.org
Oct
3
revised What gaseous substances do humans emit?
"waste" makes an pre-existing inference on function
Oct
3
suggested suggested edit on What gaseous substances do humans emit?
Oct
3
comment Is it possible to increase lifespan through controlled evolution?
The well quantifiable subject of say e.coli evolution is a totally different matter than say human evolution on aging, no less. This subject in the way it is phrased may be better suited for skeptics.SE (which is meant to discuss the information provided by notable sources).
Oct
3
awarded  Critic
Oct
3
awarded  Citizen Patrol
Oct
2
answered methods for targetted deletion of genomic regions?
Oct
1
awarded  Commentator
Oct
1
comment Brain response frequencies while sleeping
On a less serious sidenote: I know Francis Crick was an advocate of his brain@40Hz theory. / I would advocate for the Sceptics.SE site, which deals with scrutinizing notable sources...
Oct
1
answered If the brain has no pain receptors, how come you can get a headache?
Oct
1
comment Are there any substance that are more dangerous at low dose than at higher dose?
No. The influence of dose–response relationship on toxicity is one of the fundamental properties of (bio)chemistry...?!?
Oct
1
answered How do cells “know” what “type” to differentiate into?
Sep
30
answered Do Yeast Insertion constructs revert?
Sep
29
revised Are there any substance that are more dangerous at low dose than at higher dose?
-typo; rem. entirely
Sep
29
comment Are there any substance that are more dangerous at low dose than at higher dose?
Correct, I didn't include a specific example only an example mechanism. Substances acting differently at different levels is well known within the concerned fields of science. Substances/Drugs which are toxic at low levels cannot be approved nor are they generally appealing for studies. Substance's "dualism" can offset the LD50. The post also doesn't discuss how substances can be toxic at low dose or discerns entantiomeric purity (e.g. thalidomide) and/or entantiomer-specific pathways. Specific examples may best be extrapolated from systems-biological and/or chemotherapeutics literature...
Sep
28
revised Are there any substance that are more dangerous at low dose than at higher dose?
added 10 characters in body
Sep
28
answered Are there any substance that are more dangerous at low dose than at higher dose?
Sep
28
comment How are babies born without a brain?
good catch! I find the formation of the eyesockets striking. I am puzzled whether this is within the range of developmental plasticity as the result from different biomechanical forces due to craniosynostosis (premature skull fusion) OR if mutant genes (and/or pleiotrophies) are involved. OMIM unfortunately shows a practical lack of animal models. On a sidenote, the related spina bifida is known to interfere with the "eye" (opthalmic) devleopment....
Sep
28
revised How are babies born without a brain?
rephrasing
Sep
28
comment Why do carrots spoil so fast?
@Andrei Initially I wanted to explain that in the post as well and include storage conditions. But I consider it best to just ask one question at a time. Regardless, did you have consistently success w. long-term fridge storage?