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Dec
15
comment What is the benefit of near-emptying the bloodstream in the mammalian kidney?
I've spent a while thinking about this, but it makes a lot of sense, and before I read this answer, I was thinking along similar lines. With the time that changes due to natural selection take, it must make sense to remove everything that isn't exactly what it needs, so newly synthesised or evolved poisons can still be removed, even without the body knowing their sturcuture.
Oct
8
comment If proteins have an overall charge, how do membrane proteins traverse through the hydrophobic region of the plasma membrane?
And, building on that, how does the charged element of the protein pass through the membrane after synthesis to create a protein which protrudes through both sides of the membrane?
Oct
8
comment If proteins have an overall charge, how do membrane proteins traverse through the hydrophobic region of the plasma membrane?
So does the overall charge on the macromolecule not have any effect if part of it is uncharged?