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seen Oct 3 at 19:48

Not to be offended


Oct
28
awarded  Popular Question
Oct
27
awarded  Yearling
Sep
24
awarded  Autobiographer
Aug
3
comment In Japan, the official average body temperature is 36.0 °C. Why so different from that of Europe?
I was thinking "front" is a part of a head above an eyes: en.wikipedia.org/wiki/Forehead Sorry I am not native English.
Aug
3
comment In Japan, the official average body temperature is 36.0 °C. Why so different from that of Europe?
@daniel Where did you read that?
Jul
2
awarded  Curious
Jun
23
revised What is doubling of genetic material invented in flowering plants?
added 279 characters in body
Jun
19
asked What is doubling of genetic material invented in flowering plants?
May
8
comment Why cancer mutations do accumulate sequentially?
ok I agree, that mutations should not appear in one sequence, but they should appear by one. Why? See my update 2 pls
May
8
revised Why cancer mutations do accumulate sequentially?
added 663 characters in body
May
8
comment Why cancer mutations do accumulate sequentially?
I can't imagine how malignant mutations can be viable by one but not viable in sequence (and, finally, fatal if 6).
May
6
revised Why cancer mutations do accumulate sequentially?
added 212 characters in body
May
6
comment Why cancer mutations do accumulate sequentially?
But any graph of any cancer incidence is not linear. While any number of required random mutations would give flat graph. For example, if we require 3 mutations with probabilities of P1, P2 and P3 respectively, then graph will be P(t) = P1*P2*P3 = const. I.e. the probability that required 3 mutations occur simultaneously. To have curved plot, we need that mutations be not independent.
May
6
comment Why cancer mutations do accumulate sequentially?
Sorry, didn't understand. How threshold makes power dependence on age? If we observe 6th power, then we need 6 thresholds.
May
6
accepted Is it firmly established, that mutations are sufficient for cancer?
May
6
comment Is it firmly established, that mutations are sufficient for cancer?
See next question pls biology.stackexchange.com/questions/17208/…
May
6
asked Why cancer mutations do accumulate sequentially?
May
6
comment Is it firmly established, that mutations are sufficient for cancer?
I was thinking of this, and have more questions...
May
6
comment Is it firmly established, that mutations are sufficient for cancer?
@Chris, so what can you say?
May
6
comment Is it firmly established, that mutations are sufficient for cancer?
For example, I speculate, that immune tolerance is controlled by suppressor cells, that are antigen specific. I.e. for each tissue, which is not causing immune response, there is a specific suppressor population. If extra suppressors appear, then immune system become tolerant for cancer. If mutation occurs after that, then cancer develops. Contrary: if kill specific suppressor population, cancer will regress.