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seen Jun 23 at 8:49

Not to be offended


May
8
comment Why cancer mutations do accumulate sequentially?
ok I agree, that mutations should not appear in one sequence, but they should appear by one. Why? See my update 2 pls
May
8
comment Why cancer mutations do accumulate sequentially?
I can't imagine how malignant mutations can be viable by one but not viable in sequence (and, finally, fatal if 6).
May
6
comment Why cancer mutations do accumulate sequentially?
But any graph of any cancer incidence is not linear. While any number of required random mutations would give flat graph. For example, if we require 3 mutations with probabilities of P1, P2 and P3 respectively, then graph will be P(t) = P1*P2*P3 = const. I.e. the probability that required 3 mutations occur simultaneously. To have curved plot, we need that mutations be not independent.
May
6
comment Why cancer mutations do accumulate sequentially?
Sorry, didn't understand. How threshold makes power dependence on age? If we observe 6th power, then we need 6 thresholds.
May
6
comment Is it firmly established, that mutations are sufficient for cancer?
See next question pls biology.stackexchange.com/questions/17208/…
May
6
comment Is it firmly established, that mutations are sufficient for cancer?
I was thinking of this, and have more questions...
May
6
comment Is it firmly established, that mutations are sufficient for cancer?
@Chris, so what can you say?
May
6
comment Is it firmly established, that mutations are sufficient for cancer?
For example, I speculate, that immune tolerance is controlled by suppressor cells, that are antigen specific. I.e. for each tissue, which is not causing immune response, there is a specific suppressor population. If extra suppressors appear, then immune system become tolerant for cancer. If mutation occurs after that, then cancer develops. Contrary: if kill specific suppressor population, cancer will regress.
May
6
comment Is it firmly established, that mutations are sufficient for cancer?
Does not matter, but I can imagine some.
May
2
comment How well supported is the hypothesis that aging is mainly caused by the number of mutations in tissues?
The article says telomeres are shortening in stem cells too (par. 5 end). Is this true? I read stem cells have telomerase working, which is preventing telomere shortening?
Mar
12
comment Why do humans find baby animals cute?
Yes thanks, but opposition is still stronger :)
Mar
11
comment Why do humans find baby animals cute?
Don't see upvoting.
Mar
11
comment Why do humans find baby animals cute?
I can't ask them, but I can observe their behavior. If weak child died because he cannot consume food, there was no behavior, directed against him. But if child was pushed out the nest by other child -- antipathy behavior was explicit.
Mar
11
comment Why do humans find baby animals cute?
We were speaking about explicit sympathy and antipathy. Implicit degrading of weak children is not the topic.
Mar
10
comment Why do humans find baby animals cute?
Where do you see competition between children, in which animals? Usually children are fighting to train, but not to kill each other. Competition is low even between adults of the same specie.
Mar
10
comment Why do humans find baby animals cute?
So, you think liking animal babies is a side effect of liking our own babies? But if this behavior would disadvantageous, it would eliminated by evolution. Remember about cuckoo, which hates foreign babies. Obviously, hormones you are speculating about, can be much more specific, causing love to own babies and hate to foreign.
Mar
10
comment Why do humans find baby animals cute?
Domestication requires caring when babies. Human species, which didn't like animal babies, didn't domesticate anybody and failed competition with human species which did like babies. We are descendant of latter.
Nov
3
comment How was the heritability of IQ tested?
P.S. Explanation about what is child abandonment en.wikipedia.org/wiki/Child_abandonment
Nov
3
comment How was the heritability of IQ tested?
My question is how verbal (educational) inheritance was excluded. Your answer is it wasn't at all? Comparing monozygotic and dizigotic twins does not help to exclude education. Monozygotic twins can show lower variation just because they respond to education similarly.
Oct
30
comment Are all body atoms really recycled several times during a life?
But how do we know that other atoms are turned over? May be ribosome or cytoskeleton proteins are also persist?