2,831 reputation
521
bio website
location Cambridge, United Kingdom
age 29
visits member for 2 years, 4 months
seen Apr 14 at 8:43

I’m a bioinformatics PhD student at EMBL-EBI and the University of Cambridge but I’m originally from Berlin.

I’m mainly working on genomics using next-generation sequencing data. My current thesis project is about the regulation of tRNA expression in mammals.

Here’s my …

twitter-pic Twitter account
g+-pic Google+ account
github-pic Github account
cv-pic Resume


Jul
3
comment Can extinct animals be cloned?
@GriffinEvo You shouldn’t add content like this to other answers – instead, post your own answer.
Jul
3
comment What is the viability of Intelligent Design as a supplement to chemical abiogenesis and Darwinian Evolution?
Oh boy. @Bitwise, that’s a pretty bad article, even the title gets it wrong – ENCODE does not claim that junk DNA is “vital to life”. The “80% is functional” claim says nothing about necessity of that function. If ENCODE had made this claim (and if it were correct) then it’s true that the ID proponents in the 60s would have made a correct prediction (albeit for the wrong reasons). As it happens, this claim is a strawman.
Jul
3
comment How does ubiquitin recognize misfolded proteins?
That’s just begging the question. Now OP knows that ubiquitin doesn’t tag the proteins itself but they still don’t know how proteins are tagged, i.e. how E3 recognises the misfolded proteins.
May
31
comment Can extinct animals be cloned?
“you cannot preserve DNA for millions of years” – any evidence for that? I know for a fact that plenty of respectable biologists think the opposite.
May
9
comment Why are there no wheeled animals?
His Dark Materials gives a good answer to this (spoiler: it has wheeled animals)
Apr
30
comment BLAST DNA Sequences Reversed
@Alan No need for that, a simple console command does the same for you: (tr ACGT TGCA | rev) <<< 'GATTACA'
Jan
28
comment Why people like to see pornographic scenes, but do not feel the same about eating scenes?
@octern And yet I don’t see a multi-billion dollar industry around food videos. Sure there are cooking shows but their economic relevance compared to pornography … is … to say the least … you see?
Jan
28
comment Human evolution: Where *exactly* did the first human come from, whose parents were not?
@shigeta I’m uncertain – a single individual with a mutation does not a species make. That said, speciation can be fairly abrupt simply because (separated) subpopulations have to respond to sudden changes in environment.
Jan
28
revised Human evolution: Where *exactly* did the first human come from, whose parents were not?
deleted 1 characters in body
Jan
21
comment Refutation of Darwin's Random Evolution Theory
@user1909257 I think your stumbling block is that you don’t account for the vast time span involved. I’s very hard to grasp how much time evolution had. We can estimate the rate of evolution from experiments and observation, and let me tell you, even though evolution is happening really slowly, there was plenty of time since the beginning of the world. It’s simply unimaginable how old Earth is. The book Climbing Mount Improbable illustrates how tiny changes can accumulate over time.
Jan
4
comment What are the biological mechanisms behind the increase in cancer risk and alcohol consumption?
Am I missing something here or is it just for the rather obvious reason that alcohol is a strong cell toxin that, taken often, causes constant low-level inflammation and stress (and thus accumulating damage) in tissues?
Jan
4
comment Can cancer grow forever if supplied with unlimited resources?
@leonardo In my understanding most cancer cell lines are in fact not immortal. When they found that HeLa wasn’t dying they had in fact already been searching for an immortal cell line for quite some time without success, and finding HeLa was a big surprise.
Jan
4
comment Why is the frog genome so much larger than a fish's?
I think the last paragraph nails it (and, incidentally, the controversy about ENCODE’s 80% figure) – although intronic DNA is just a small part, much more is in repeat elements.
Jan
4
comment Why is the frog genome so much larger than a fish's?
I think this question, like at least a few others, is based on a misunderstanding of ENCODE’s use of the word “function”. Maybe we should have a kind of FAQ for that. (Disclaimer: I agree with their usage of the word. Others, e.g. Larry Moran, disagree – vehemently.)
Dec
18
awarded  Yearling
Dec
17
comment How to map the Gene name to its Gene Symbol?
Well, I agree that it’s a nuisance but we have stable identifiers (= don’t change) and services to translate between the different ones. It’s a solved problem (in that it may still require manual work, but not intellectual work).
Dec
17
answered How to map the Gene name to its Gene Symbol?
Dec
17
comment How to map the Gene name to its Gene Symbol?
“one of the greatest problems” – uh.
Dec
17
revised Why does the cold make us sick?
Typography
Nov
21
comment Can species back-evolve?
@Andrei I agree with your (implicit) points about cognition and, what Popper has termed, “world 3”. However, this is strictly outside of the scope of biological evolution (even though it’s a consequence). The “aim” of evolution is simply: to reproduce. This is the only measure of evolutionary fitness that counts. And by this measure, humans are usually not better, and sometimes worse, off than other species.