2,826 reputation
521
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location Cambridge, United Kingdom
age 29
visits member for 2 years, 4 months
seen Apr 14 at 8:43

I’m a bioinformatics PhD student at EMBL-EBI and the University of Cambridge but I’m originally from Berlin.

I’m mainly working on genomics using next-generation sequencing data. My current thesis project is about the regulation of tRNA expression in mammals.

Here’s my …

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Mar
23
comment How did the first sexual animal come to exist?
Actually your text already convinced me, concerning the number of times sex evolved (hence the edit).
Mar
23
comment How did the first sexual animal come to exist?
I’m not sure I would agree with “no brainer”. As far as I know, sexuality has only evolved once. Also, could you expand a bit on the heterogamy argument? In particular, wouldn’t the same apply to plasmids? Yet we don’t see anything particularly resembling sexual selection emerge from that. /EDIT: Your answer might actually contradict my first assertion (I should have read the full post first) – I’m still interested in an answer to the second.
Mar
23
comment How did the first sexual animal come to exist?
I’ve had to edit your answer, “just one theory” sounds a bit too similar to the “just a theory” creationist canard for comfort. I’m wary that it might feed the common misconceptions about what makes a scientific theory.
Feb
22
comment Why is Portuguese man o' war considered a colony?
@har-wradim I seem to have misinterpreted what scarce information I could find about siphonophorae. Thanks for the link. Having said that, a cursory reading of the article actually seems to support my understanding (although the “develop independently” part of my answer is certainly imprecise and suggest that they assemble into colonies after embryogenesis). I need to spend more time on this.
Feb
20
comment Aren't current explanations for the evolution of human cooperation a little too reductionist?
Inclusive fitness proponents will tell you that this explanation is completely wrong, by they way (without being an expert, I tend to agree).
Dec
26
comment Why has evolution made neurons use spiking?
You should read up on how neurons work. You admitted that you don’t know this, yet it directly answers your question.
Dec
24
comment Why it is rare for person to get infected with two Pathogens?
Your example is actually quite bad because the “common cold” is often an infection by several strains of viruses (and even bacteria) simultaneously.
Dec
21
comment Is light required for seed germination?
The riddle can be solved by realising that different plants have different requirements, and that some requirements are “soft” – i.e. not absolutely necessary but nevertheless beneficial. I’ll let somebody else with more knowledge provide a more in-depth answer – my comment wasn’t meant to imply that this is a bad question.
Dec
21
comment Is light required for seed germination?
Given that germination often happens underground, the answer seems trivially “no”, doesn’t it?
Dec
7
comment How easy is it to carry out de novo sequence assembly?
tl;dr: It’s blood, sweat and tears. I haven’t been involved in this myself yet but I know people who are. Depending on the complexity of the genome, you’ll get tons (they got in the order of 1M) non-overlapping contigs.
Sep
13
comment Why are there no wheeled animals?
@terdon Hehe, and I likewise forgot about the G’Kek. But re-reading the Uplift Saga is time well spent anyway. ;-)
Jul
8
comment Does evolution destroy functional sequences much faster than it creates them in any large-genome animal with low reproductive rates?
Biology.SE is actually very unhappy about creationism questions. However, I think this one’ll pass.
Jul
3
comment Can extinct animals be cloned?
@GriffinEvo You shouldn’t add content like this to other answers – instead, post your own answer.
Jul
3
comment What is the viability of Intelligent Design as a supplement to chemical abiogenesis and Darwinian Evolution?
Oh boy. @Bitwise, that’s a pretty bad article, even the title gets it wrong – ENCODE does not claim that junk DNA is “vital to life”. The “80% is functional” claim says nothing about necessity of that function. If ENCODE had made this claim (and if it were correct) then it’s true that the ID proponents in the 60s would have made a correct prediction (albeit for the wrong reasons). As it happens, this claim is a strawman.
Jul
3
comment How does ubiquitin recognize misfolded proteins?
That’s just begging the question. Now OP knows that ubiquitin doesn’t tag the proteins itself but they still don’t know how proteins are tagged, i.e. how E3 recognises the misfolded proteins.
May
31
comment Can extinct animals be cloned?
“you cannot preserve DNA for millions of years” – any evidence for that? I know for a fact that plenty of respectable biologists think the opposite.
May
9
comment Why are there no wheeled animals?
His Dark Materials gives a good answer to this (spoiler: it has wheeled animals)
Apr
30
comment BLAST DNA Sequences Reversed
@Alan No need for that, a simple console command does the same for you: (tr ACGT TGCA | rev) <<< 'GATTACA'
Jan
28
comment Why people like to see pornographic scenes, but do not feel the same about eating scenes?
@octern And yet I don’t see a multi-billion dollar industry around food videos. Sure there are cooking shows but their economic relevance compared to pornography … is … to say the least … you see?
Jan
28
comment Human evolution: Where *exactly* did the first human come from, whose parents were not?
@shigeta I’m uncertain – a single individual with a mutation does not a species make. That said, speciation can be fairly abrupt simply because (separated) subpopulations have to respond to sudden changes in environment.