583 reputation
26
bio website
location United States
age
visits member for 2 years, 9 months
seen Aug 25 at 16:56

I am a computational biologist at Genentech broadly working in oncology drug discovery.


Dec
21
awarded  Yearling
Aug
8
comment What is genomic imprinting?
Have you read the wikipedia entry for genomic imprinting?
Jun
20
revised Transcriptionally-mediated DNA damage
Added links to referenced papers
Jun
20
suggested suggested edit on Transcriptionally-mediated DNA damage
Jun
17
revised Information Gene HBA2
added 77 characters in body
Jun
17
answered Information Gene HBA2
Jun
6
comment Movement of stem cells from mother to fetus
Yes, a link to the reference would be most helpful. In the meantime, I found some abstract from a conference where they apparently presented this work here: Chimeric maternal cells as T lymphocyte targets in pediatric SLE
May
9
comment Which X-Y chromosomes have the developmental genes for mammals?
Can you clarify what "toolkit" genes you are referring to? Do you have a link/citation for the source you read about them from? I'm guessing you are not referring to the toolkit genes listed here, so a bit more clarity might be helpful.
May
2
comment How is gene expression estimated?
@leonardo: Can you clarify what you mean by MS being highly sensitive? It's my understanding that one problem with MS that you only get reliable (any) readouts for the most abundant of proteins in your sample, no?
Apr
11
comment Problems with analysis of small RNAseq data - Adapter trimming
@WYSIWYG: I suggested biostar, not seqanswers ;-) Still, this forum is less suitable simply because your question is more of a bioinformatics nature than strictly biology one -- and you will find more expertise related to bioinformatics on biostar than here. I would imagine that there are likely many people on biostar who are strong bioinformaticians that do not have accounts on this site, and you would benefit from getting their input. Consider, for example, why there are different SE sites for math and stats :-)
Apr
11
answered Problems with analysis of small RNAseq data - Adapter trimming
Mar
7
answered Combining gene expression data from two species
Feb
21
comment What are the limitations of commercial-grade DNA genotyping compared to full sequencing?
@nico: Yeah, very true. You can also get a copy of the data, though, which is cool. Also, they're also currently offering exome capture for some already existing members ... a look towards what the future may hold, perhaps.
Feb
21
revised What are the limitations of commercial-grade DNA genotyping compared to full sequencing?
fix grammar
Feb
21
answered What are the limitations of commercial-grade DNA genotyping compared to full sequencing?
Feb
12
comment Confusion related to gene expression
There are other ways to convert id's to genes. I'd be surprised if you can't query BioMart to get that answer (look in the ID Converter tab). It also looks like the DAVID website has a conversion tool that may get you what you need.
Feb
12
comment Confusion related to gene expression
I suggest you use the limma package in bioconductor to analyze the data. I'm not sure why one study has data from two chips -- it's unfortunate. You'd first have to study each batch separately, then do some meta-analysis to combine the results from each together. If you're not comfortable programming, you might try Gene Pattern, though I've never used it. Lastly: you should likely post bioinformatics related questions over on biostar.
Feb
11
answered Confusion related to gene expression
Feb
1
answered How to find Exons in mRNA Computationally
Jan
31
comment What is the best way to read and normalize large amounts of Agilent data into R?
@terdon: that wouldn't work, "the usual" array normalization methods pretty much require working on all of the data together (so it needs to be loaded in memory). That having been said, this question should definitely be asked on the bioconductor mailing-lsit, biostars.org.