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seen Aug 22 at 11:51

Apr
13
comment Chromosomes are of different size but why do all chromosomes have similar GC percentage?
I liked your line "stability and coding constraints play against each other to converge on an optimal GC content in any given stretch of the genome." It feels more suitable to my question. Can I get a reference journal please
Apr
13
awarded  Supporter
Mar
7
comment Chromosomes are of different size but why do all chromosomes have similar GC percentage?
I liked the idea of proportionality of chromosome protien coding size and genes.. thanks. Why this question made me think it is important to ask because evolution is with random mutation process and with new environmental conditions the orgamism evolves to form new genes & this will cause random huge variations but by looking at GC% information, though there might be huge variation in sequences of chromosomes, a life is conspiring to maintain an equilibrium in AT:GC ratio. life doesnt thinks It has to keep ATG at beginning and poly A tail end for gene. life just checks the equilibrium
Mar
7
revised Chromosomes are of different size but why do all chromosomes have similar GC percentage?
added 515 characters in body
Mar
7
comment Chromosomes are of different size but why do all chromosomes have similar GC percentage?
Yupp you got it... I just want to know why and how at any stage of evolution an organism like [plasmodium vivax] (ncbi.nlm.nih.gov/genome/genomes/35?details=on&) (43-47%) and faciparum (18-20%) (2 evolved types) try to maintain similar GC% in all chromosome (look a the links given the it feels all chromosomes are maintaining their GC% percent in chromosomes and they dont care for amount of genes or chromosome size)
Mar
1
awarded  Editor
Mar
1
revised Chromosomes are of different size but why do all chromosomes have similar GC percentage?
edited title
Mar
1
comment Chromosomes are of different size but why do all chromosomes have similar GC percentage?
Thanks, I truly get nucleotide composition varies significantly (A:T:C:G changes) but still HOW GC% remains similar throughout all chromosomes. To further clarify vivax (V)(43-47% range) and faciparum (F)(18-20% range) are of same plasmodium family. Eg chr 11 of both have almost same size but their GC% percent fall in particular given range(V: 45:1%, F:19%). It feels like differently evolved organism are trying to maintain particular range of GC%. HOW? And journal reference would be much appreciated.
Feb
28
awarded  Student
Feb
28
asked Chromosomes are of different size but why do all chromosomes have similar GC percentage?