552 reputation
37
bio website github.com/sopo
location Paris, France
age 25
visits member for 2 years, 4 months
seen Mar 2 '13 at 11:09

PhD student in Paris.

Working on the crosstalk of glucocorticoids and thyroid hormones at a genome wide level during the metamorphosis of the Xenopus tropicalis tadpole.

I also have some knowledge in bioinformatics, more precisely in processing and analysis of NGS data.


Dec
15
comment Transmission of epigenetic regulation through surrogate mother
You are totally right, for some reason histone variants did not come to my mind when answering :)
Dec
15
comment What are limiting factors for intron length?
I don't know about the maximum length, but I suppose that for the minimal size, the mechanical properties of the DNA are the limiting factors. Under a certain size, DNA is simply too stiff to form the loops required during splicing.
Dec
15
comment Bacterial chromatin binding data?
I'm not sure I fully get your question. Prokaryotes do not have nucleosomes.
Dec
15
answered What are the mechanism binding histone code with alternative splicing?
Dec
15
awarded  Analytical
Dec
15
awarded  Teacher
Dec
15
answered Transmission of epigenetic regulation through surrogate mother
Dec
15
awarded  Supporter
Dec
14
answered How can I avoid digesting protein-bound DNA?