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Jan
26
comment Looking for a cancer drug target database to guide sequencing of patient tumor DNA
Although, upon further reading their website, it may be possible to upgrade the machine to do this in the future by changing the chip. We are getting the machine delivered to the lab this afternoon, so I haven't actually gotten to play with it yet. If anyone else has more comments or suggestions, please let me know! Thanks.
Jan
26
comment Looking for a cancer drug target database to guide sequencing of patient tumor DNA
Thanks for the comments everyone. We have purchased an Ion PGM sequencer, which is not capable of performing whole exome sequencing. The company says that the sequencer is "ideal for sequencing small genomes, sets of genes, or performing gene expression profiling or ChIP-Seq." Researchers can interrogate "targeted genomic regions using up to 1,536 amplicons in a single tube, in a single day." Their website is www.iontorrent.com. For this reason we would like to design a panel of particular genes to sequence in each tumor type. I will check out the other websites that you all have suggested.