3,065 reputation
2940
bio website standage.github.io
location Bloomington, IN
age
visits member for 2 years, 7 months
seen Jul 17 at 15:43

Husband, father, graduate student, aspiring scientist, avid programmer, amateur technophile, flipper of pancakes, and baker of biscuits.


Apr
18
comment What exactly are computers used for in DNA sequencing?
@sharptooth I'm not sure you want to replace the word "sequencing" with the word "assembly" in the question. The answer to your question is that sequencing and assembly are closely related, and assembly is the part that requires significant computational power.
Apr
18
comment What exactly are computers used for in DNA sequencing?
Good analogy, but I would say DNA assemblers have the same problem, not sequencers.
Apr
18
comment What are the limitations to current nucleotide sequencing technologies?
@yotiao What you're saying is true, but only to a point. My experience is that assemblies and other analysis improve with coverage, but at a certain point adding more data provides only minimal improvements, even if there is a significant addition of new data. And to say that the human genome project was successful primarily because they dedicated a lot of Sanger sequencers to the project ignores the significant differences between the nature and quality of the data produced by the Sanger platform as opposed to today's high-throughput platforms.
Apr
18
answered What exactly are computers used for in DNA sequencing?
Apr
18
revised Measuring reverse transcriptase activity in E. coli
retag
Apr
17
revised What is the significance and method behind Ramachandran plots?
retag
Apr
13
revised Compressing structural information in PDB files
edited body
Apr
11
awarded  Nice Answer
Apr
11
revised How is the blood volume of a living organism measured without killing it?
fixed grammar
Apr
11
revised gene-annotation wiki excerpt
added 85 characters in body
Apr
11
revised nomenclature wiki excerpt
added 159 characters in body
Apr
11
suggested suggested edit on gene-annotation tag wiki excerpt
Apr
11
wiki created gene-annotation excerpt
Apr
11
suggested suggested edit on nomenclature tag wiki excerpt
Apr
11
wiki created nomenclature excerpt
Apr
8
revised Why do eukaryotic organisms have introns in their DNA?
retag
Apr
8
answered Why do eukaryotic organisms have introns in their DNA?
Apr
6
comment What is the difference between “dikaryotic” and “heterokaryotic” states in the sexual lifecyles of fungi?
So heterokaryon is the general case, and dikaryon is a specific case?
Apr
3
revised Are there differences in DNA between humans of today and humans from 2000 years ago?
corrected spelling
Apr
3
comment Are there differences in DNA between humans of today and humans from 2000 years ago?
It's a huge leap from "differences in DNA" to "differences in traits."