3,136 reputation
2945
bio website standage.github.io
location Bloomington, IN
age
visits member for 2 years, 9 months
seen Sep 25 at 15:33

Husband, father, graduate student, aspiring scientist, avid programmer, amateur technophile, flipper of pancakes, and baker of biscuits.


Jul
8
comment Accuracy of genome size estimation by flow cytometry
@JeremyKemball No, it's not near an integer multiple, so it's not a ploidy issue. The reasoning behind the k-mer analysis is to identify a sequence that occurs once in the genome and count how many times it occurs as a proxy for coverage. Since that unique sequence is unknown, we instead examine k-mer distributions and look for the mode in those distributions.
May
20
comment Help with the Price equation
Thanks for sharing @Sanalphatau. Rather than providing a link-only answer, we typically ask community members to provide a brief summary or excerpt of the salient point(s) from the linked material (see biology.stackexchange.com/help/referencing). If for any reason your link gets broken in the future, this answer would become useless without any additional info.
May
19
comment Evolution of Chromosome Numbers
possible duplicate of Evolutionally speaking, why do humans have 46 chromosomes
May
17
comment What is most simple eukaryotic genome?
In case you were unaware, you can (and are encouraged!) go back and edit the text of your original question. We're not trying to condemn you for the way you asked the question, just providing suggestions for how you can clarify and improve the question, for your benefit and ours.
May
17
comment What is most simple eukaryotic genome?
I have to agree with @MattDMo, this question is meaningless in its current state (which is why I downvoted it and voted to close it). The problem would be much better if you were to clarify a few things. For example, what do you mean by "most simple DNA molecule"? Are you using the term "information" in the vernacular sense or in the theoretical sense? And if by "exists today" you really meant, "naturally occurring in eukaryotic cells", then it's better to say what you really mean. Addressing these concerns will help us as a community address your question meaningfully.
Dec
6
comment What are some examples of genes that code for multiple proteins?
The top hit for a Google search for "alternative splicing" is the Wikipedia article on alternative splicing, which includes several examples. I can't imagine that any textbook that covers alternative splicing would not also offer examples.
Aug
28
comment Why is the frog genome so much larger than a fish's?
Just saw this on Twitter, and wanted to point it out. twitter.com/DanGraur/status/372712933525946368
Aug
1
comment Collective term for both exons and introns
This isn't the word I'm looking for. The word I'm looking for will fill in the following blank: "The gene has 5 exons and 4 introns, so it has 9 ____". Splicing fragments is the best answer so far, I was just hoping there was a more concise term for it.
May
3
comment Do immortal organisms exist?
Umm, that was supposed to be a joke...
May
2
comment Do immortal organisms exist?
If you're referring to the elves of Middle Earth, I'm sorry no they do not exist.
May
2
comment Do marine deep sea life forms exhibit circadian rhythms? If so, what entrains them?
This, IMHO, is an excellent question.
Mar
20
comment Why is that all the animals can swim in water without learning to swim but humans cannot?
Can you back up the assertion that all mammals can swim without being taught?
Mar
1
comment How do amino acids become attached to tRNA?
@ohcanada, sorry for blowing off your suggested edit. I should have given the original question and your suggestion more consideration.
Dec
14
comment Why does the cold make us sick?
This is a comment based on anecdote, so I don't feel comfortable listing it as an answer. But one explanation I have heard is that much of the sickness we see during the colder season(s) is not the result of our bodies actually being in the cold, but the result of spending more time indoors sharing each other's germs rather than being outdoors in the fresh air.
Dec
1
comment 3D models of adult male brain in the Blender software? Any open-sourced version for research?
<childishness>Am I the only one who initially (mis)read "adult male brain in a blender"? :)</childishness>
Nov
29
comment Comparative cost of RNA-seq vs sequencing full length cDNAs
"Do you have a specific goal?" The PI of this genome project is primarily interested in the intersection of evolution, genomics, and behavior, and uses several species of social insects as model organisms for these subjects.
Nov
29
comment Comparative cost of RNA-seq vs sequencing full length cDNAs
"What kind of organism?" It's eukaryotic, a social insect to be precise. "Is there a good existing reference genome for you organism?" As I said, this is a non-model species, so I am the one assembling the genome. I don't know what your criteria are for a "good" genome: no physical mapping, gap filling, etc has been done yet, but the assembled sequence is close to the expected genome size and preliminary annotations have identified about the number of genes we would expect (perhaps a little bit less).
Nov
29
comment Would two species of yeast with similar genome sizes have the same number of genes or chromosomes?
I'm doubtful regarding your premise. See my related comment on this thread.
Nov
15
comment Could a fetus properly develop in micro/zero-gravity?
Let me just say, it would be awesome to be the first scientist to breed mice in space. Just sayin...
Sep
20
comment Transcript(omics) terminology: cDNAs, ESTs, RNA-seq, etc
When I said "short reads", I was referring in that case to RNAseq reads. Of course, in general short reads can be genomic (if you're sequencing the genome) or transcriptomic (if you're doing RNAseq analysis or something similar).