3,024 reputation
2938
bio website standage.github.io
location Bloomington, IN
age
visits member for 2 years, 4 months
seen 2 days ago

Husband, father, graduate student, aspiring scientist, avid programmer, amateur technophile, flipper of pancakes, and baker of biscuits.


Dec
6
comment What are some examples of genes that code for multiple proteins?
The top hit for a Google search for "alternative splicing" is the Wikipedia article on alternative splicing, which includes several examples. I can't imagine that any textbook that covers alternative splicing would not also offer examples.
Sep
10
comment Which organisms have the most appendages?
Anthropocentric, simplistic, and arbitrary.
Aug
28
comment Why is the frog genome so much larger than a fish's?
Just saw this on Twitter, and wanted to point it out. twitter.com/DanGraur/status/372712933525946368
Aug
1
comment Collective term for both exons and introns
This isn't the word I'm looking for. The word I'm looking for will fill in the following blank: "The gene has 5 exons and 4 introns, so it has 9 ____". Splicing fragments is the best answer so far, I was just hoping there was a more concise term for it.
May
3
comment Do immortal organisms exist?
Umm, that was supposed to be a joke...
May
2
comment Do immortal organisms exist?
If you're referring to the elves of Middle Earth, I'm sorry no they do not exist.
May
2
comment Do marine deep sea life forms exhibit circadian rhythms? If so, what entrains them?
This, IMHO, is an excellent question.
Mar
20
comment Why is that all the animals can swim in water without learning to swim but humans cannot?
Can you back up the assertion that all mammals can swim without being taught?
Mar
1
comment How do amino acids become attached to tRNA?
@ohcanada, sorry for blowing off your suggested edit. I should have given the original question and your suggestion more consideration.
Dec
14
comment Why does the cold make us sick?
This is a comment based on anecdote, so I don't feel comfortable listing it as an answer. But one explanation I have heard is that much of the sickness we see during the colder season(s) is not the result of our bodies actually being in the cold, but the result of spending more time indoors sharing each other's germs rather than being outdoors in the fresh air.
Dec
1
comment 3D models of adult male brain in the Blender software? Any open-sourced version for research?
<childishness>Am I the only one who initially (mis)read "adult male brain in a blender"? :)</childishness>
Nov
29
comment Comparative cost of RNA-seq vs sequencing full length cDNAs
"Do you have a specific goal?" The PI of this genome project is primarily interested in the intersection of evolution, genomics, and behavior, and uses several species of social insects as model organisms for these subjects.
Nov
29
comment Comparative cost of RNA-seq vs sequencing full length cDNAs
"What kind of organism?" It's eukaryotic, a social insect to be precise. "Is there a good existing reference genome for you organism?" As I said, this is a non-model species, so I am the one assembling the genome. I don't know what your criteria are for a "good" genome: no physical mapping, gap filling, etc has been done yet, but the assembled sequence is close to the expected genome size and preliminary annotations have identified about the number of genes we would expect (perhaps a little bit less).
Nov
29
comment Would two species of yeast with similar genome sizes have the same number of genes or chromosomes?
I'm doubtful regarding your premise. See my related comment on this thread.
Nov
15
comment Could a fetus properly develop in micro/zero-gravity?
Let me just say, it would be awesome to be the first scientist to breed mice in space. Just sayin...
Sep
20
comment Transcript(omics) terminology: cDNAs, ESTs, RNA-seq, etc
When I said "short reads", I was referring in that case to RNAseq reads. Of course, in general short reads can be genomic (if you're sequencing the genome) or transcriptomic (if you're doing RNAseq analysis or something similar).
Sep
20
comment In the vacuum of space would death be instantaneous?
"While explosive decompression has never been tested on humans..." Love it!
Sep
20
comment In the vacuum of space would death be instantaneous?
Sounds like a perfect candidate for what-if.xkcd.com! :)
Sep
19
comment Transcript(omics) terminology: cDNAs, ESTs, RNA-seq, etc
Ok, perhaps my use of "often" is biased by my own experience. I am working on genome annotation, and both the Maker annotation pipeline and some of our in-house workflows require RNA-seq data to be assembled before they can be used as evidence when predicting gene models. I understand of course when mapping short reads to a genome or quantifying gene expression, assembly is not a prerequisite.
Sep
18
comment Foveal ganglion cell density (Tay-Sachs Disease)
+1 This appears to be an excellent and thorough answer, although it is a lot of material to post without citing any primary literature.