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Apr
2
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Mar
7
comment Is there a standard reference for the importance of tumor heterogeneity?
Welcome to the site! Do you know any other sources for Alexandrova's essay apart from a dropbox link? I know a lot of people are unwilling to click those. Also, could you make your answer a bit more self-contained by taking a reference or two out of Alexandrova's essay for when you say "has been around for a long time", for example? That way people can have an idea of the timeline without having to leave this answer.
Mar
5
revised Assumptions of Hamilton's rule
added 210 characters in body
Mar
5
answered Assumptions of Hamilton's rule
Mar
5
comment Is there a standard reference for the importance of tumor heterogeneity?
That paper is very well cited (over 1000 times!), but I agree with @WYSIWYG that 2012 seems too recent. Is there a richer history with Gerlinger and Swanton that you could expand on in your answer? Or did you intend this as a comment?
Mar
5
asked Is there a standard reference for the importance of tumor heterogeneity?
Mar
2
comment What is the creature with the lowest neuron count that demonstrates cognition beyond reflexes?
Depending what you mean by cognition, it could be zero.
Feb
24
awarded  Announcer
Feb
23
comment Does a neuron ever generate an action potential without stimuli?
You might be interested in this quetions on neurons firing 'randomly'.
Feb
17
comment Natural examples of XOR functions at the cellular level
@WYSIWYG Keep in mind, that a clock/counter is not that great an analogy, since we want the circuit to combine several different input wires/signals and not just track one.
Feb
17
comment Natural examples of XOR functions at the cellular level
@WYSIWYG what are the empirical examples you have in mind? Are they still from synthetic biology? Right now I am following some leads by looking at mechanisms of co-inhibition in T cells, but my lack of knowledge (and other commitments) are making my progress slow. I am not sure if we have to look for binary adders, necessarily. That is just a particular way of thinking about it. However, if we want to go the adders route then base doesn't matter, any prime will work, so an application could be time/season/period tracking.
Feb
17
comment Does this equation have a typo? (Systems Biology, singular value decomposition)
(a) this question has nothing to do with biology (although the paper obviously does, no biology is featured in the question) and (b) yes, it is a typo, as you can tell from it being $x_m$ and not $x_r$ and also as you can tell from equation 6 properly having $v_{k,n}$.
Feb
16
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Feb
16
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Feb
16
reviewed Approve What would happen if you combined the world's deadliest diseases & viruses?
Feb
15
awarded  Announcer
Feb
15
revised Natural examples of XOR functions at the cellular level
added a link and fixed up some references.
Feb
15
comment Does neuroeconomics study the brain or study economics?
You should consider asking this question on the cognitive sciences stackexchange, which specializes in neuroscience and related fields.
Feb
15
comment Evolution, self organization and neuroscience
I recommend looking at Hoffman's interface theory of perception to help you explore some of the assumptions you are implicitly making in your question. Also, just because a fitness peak exists, doesn't mean you'll get there (for any reasonable notion of getting there).
Feb
15
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