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location Boston, MA USA
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visits member for 2 years, 8 months
seen Jun 13 '13 at 13:30

May
21
revised The evolution of dogs through domestication and artificial selection
added 349 characters in body
May
21
answered The evolution of dogs through domestication and artificial selection
May
21
comment The evolution of dogs through domestication and artificial selection
+1 for the fox example! This shows how few genetic polymorphisms and how fast domestication (ie, taming) can occur. Other studies have shown that a few genetic polymorphisms can lengthen snout, shorten legs, alter other characteristics which are used to distinguish a breed of dog.
May
15
revised Is there any difference in terms of personal healthcare between complete DNA sequencing and SNPs genotyping?
added 333 characters in body
May
11
comment obesity risk and single gene polymorphisms
Yes, FTO is the strongest thus far in the populations thus far tested. If Asians or African populations were to be tested as deeply, as often as European populations, other genes certainly may be added to the list.
May
11
comment Is there any difference in terms of personal healthcare between complete DNA sequencing and SNPs genotyping?
Sequencing gives the researcher data on rare or private mutations that are not on the genotyping arrays.
May
10
answered Is there any difference in terms of personal healthcare between complete DNA sequencing and SNPs genotyping?
May
8
comment Primary function of the enzyme lipoprotein lipase
No. All cells need fats, primarily to build membranes and to store in vesicles for later conversion to energy. Storage is not restricted to adipocytes.
May
4
answered How did the human brain evolve?
May
3
revised Genetic effects on personality
added 16 characters in body
May
1
comment Linkage and LD: quantitative or qualitative?
This is a good explanation with a fine example. It can be added that the r^2 value can be between 1 (complete LD) and 0 (zero, no LD whatsoever as with markers on different chromosomes). Yes, we and many others use a cutoff of r^2 > 0.8 to denote strong LD. However, values of 0.4 and above are not to be discounted as having no LD.
Apr
30
answered Is it possible to live without health problems sleeping one day and not the other?
Apr
30
revised Is it possible to live without health problems sleeping one day and not the other?
edited tags
Apr
30
answered Which functional annotations could be useful?
Apr
27
answered Relationship between our microbiome and personalized nutrition
Apr
26
answered Genetic effects on personality
Apr
26
comment How many genes do we share with our mother?
I like the physical vs abstract take on this.
Apr
26
comment How many genes do we share with our mother?
Nice answer, +1. Actually, recent analysis of 1000 Genomes data shows that each person has some 25-40 homozygous LOF (loss of function) variants not found in either parent. Thus, one could lower the 100% figure to ~99.9% shared.
Apr
23
answered Consensus codon optimization by organism
Apr
23
comment Mouse meta-globin mRNA problem
A) Is this a take-home exam question? 1) Yes, then I can't answer your questions for you. 2) No, well, I'll see if I have time tomorrow to get to it.