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Oct
21
revised How are Genetic Circuits Modelled?
Fixed link.
Oct
21
comment How realistic is to use DNA for long term storage?
Further more, Harvard researchers have used DNA to encode 700 TB of binary information into a single gram of dsDNA. hms.harvard.edu/content/writing-book-dna
Oct
21
asked How are Genetic Circuits Modelled?
Oct
21
comment How realistic is to use DNA for long term storage?
EDIT: 521 years, radiocarbon dated from bone fossils, specifically measuring mtDNA. (rspb.royalsocietypublishing.org/content/early/2012/10/05/…;. That said, dried DNA is orders of magnitude more stable at room temp than solubilized DNA, so the longevity of DNA for storage, when the conditions are not specified, can vary widely.
Oct
21
comment How realistic is to use DNA for long term storage?
I seem to recall a recent report that DNA had a half-life of 517 years. I don't know the conditions under which this was tested. I'll look up the reference and post it here.
Oct
21
comment Why do drugs which are hormones have long half-life?
That's also true. These formulations are often modified fpo that they still activate the receptor but resist enzymatic degradation so diabetics can use less insulin, less frequently.
Oct
20
comment Why does high-voltage mostly shock a person, and even small current kill?
I think the real answer here is not simply current or voltage, but rather the power and duration (energy) deposited through the body. Neither high-current nor high-voltage are necessarily fatal by themselves, just like low-voltage or low-current can be fatal. The greather the voltage and/or current, and the longer it is applied to the body, applied to sensitive areas (eg, brain, heart), the more likely it is to be fatal.
Oct
20
comment What is the difference between orthologs, paralogs and homologs?
I modified your answer to be less forceful in its statement that terdon took issue with. If you don't agree with it, you can reject the change.
Oct
20
revised What is the difference between orthologs, paralogs and homologs?
Edited statement in accordance with commends below. Clarified grammar.
Oct
20
comment Why do drugs which are hormones have long half-life?
This is a good, broad answer to the OP's question. I would add, for protein hormones at least, they tend to be secreted as autocrine/paracrine/endocrine hormones, and by definition need only carry a signal for a brief period of time before the hormone is degraded (otherwise signalling would go on for longer than is necessary). For example, insulin has a half-life of on the order of minutes.
Oct
19
comment Why do drugs which are hormones have long half-life?
Peptide hormones have short half-lives because there are enzymes in blood plasma to degrade them. Half-life of any substance depends on, among other things, their route of metabolism and delivery.
Oct
19
comment Can I image Coomassie and GFP in gels at the same time with a fluorescence scanner?
Can you explain how you get actual fluorescence images from your gels in which GFP is denatured?
Oct
17
awarded  Excavator
Oct
17
comment How many human proteins have a solved 3D structure?
This is a very subject question for two reasons: The Protein Databank accepts NMR and crystal structures of proteins which offer different degrees of resolution and accuracy. These structures are also somewhat subjective because the protein may adopt different conformations depending its relevant biological context. Thirdly, the solvent extractions may impose erroneous structure.
Oct
17
revised What effect has changing pH and salt concentration on protein complexes?
Fixed typo.
Oct
17
accepted Finding and Comparing Homologous Genes
Oct
17
comment Are there any websites offering graphs for the light absorption of different enzymes?
@rwst - This is true, and is only possible if an in vitro assay for enzyme activity exists. It also relies on the purified enzyme being active, which is not always the case. The question asked was more broadly stated.
Oct
17
comment Are there any websites offering graphs for the light absorption of different enzymes?
@AbdelrahmanEsmat - they don't need to know specific information about the enzyme (or any protein's) absorbance because it is inferred based on knowledge of how amino acids absorb light at specific wavelengths.
Oct
17
comment Genetic engineering for insulin production
@Bitwise, January - I stand corrected. I meant to say the modifications from eukaryotic cells is different. :)
Oct
16
awarded  Custodian