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"Live a good life. If there are gods and they are just, they will not care how devout you have been, but will welcome you based on the values you have lived by. If there are gods, but unjust, then you should not want to worship them. If there are no gods, then you will be gone, but will have lived a noble life that will live on in the memory of your loved ones. I am not afraid."

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Aug
4
awarded  Necromancer
Jul
31
awarded  Civic Duty
Jul
26
awarded  Enlightened
Jul
26
awarded  Nice Answer
Jul
26
comment Computational/mathematical models for predicting phenotype from genotype
@ArtemKaznatcheev Ok, but I don't really see how you could quantify the effect you are having on the outcome without making a specific change at the molecular level. What is it you would actually like to measure, and what it is you would actually like to 'alter' to see an effect? Thanks!
Jul
26
answered Cell proliferation limit and senescence of embryonic stem cells and fibroblasts
Jul
26
comment Computational/mathematical models for predicting phenotype from genotype
@ArtemKaznatcheev the paper you cited describes a model that uses many different molecular phenotypes to build a 'model' of whether cellular functions are affected by gene perturbations. Bob has cited several viable options for you to do a simplified model in E.coli, however if these do not help in answering your question then it may need re-phrasing.
Jul
26
comment What negative effects can pinhole glasses have on the body?
interesting answer, well reasoned, but do you have any references (e.g. for the infants being born without perfect vision)? I agree that these could definitely be argued to reduce your field of vision, and thus be unsafe for driving, but if you can find a study into this that would be ideal
Jul
26
comment What negative effects can pinhole glasses have on the body?
Did you try them on by any chance?
Jul
26
comment Are mature trees as susceptible to mutation from exposure to radiation as seedlings?
Ben raises a good point about this question actually - @Everyone are you interested in the effect of radiation on a single cell sampled from a large tree (compared to a single cell in a sapling), or on the organisms as a whole? If it is the whole organisms, Ben has the correct answer I believe; mutations (and thus radiation) will be less of a problem to a plant once it is larger, as any cutting of the plant could go on to form a new tree; each individual cell becomes less important. (See biology.stackexchange.com/questions/2055/… out of interest)
Jul
26
comment Black bumps on the cut surface of an avocado
+1, interesting reasoning.
Jul
26
comment Is there a correlation between incidence of type 1 diabetes and vitiligo?
References to papers? If there isn't one on the wiki page with the statements, I would be less than happy to vote this up. Also, if CD4 mutations been found to cause both diseases, is there any observational evidence (epidemiology) you have found whilst reading? It does seem likely they are related as they are both autoimmune diseases of the T-cells, but they may have independent mechanisms of action via CD4 (etc), so disease incidence may not be correlated.
Jul
25
answered What is the “lifecycle” of an average eschar and what types of cells are involved in each stage?
Jul
21
comment Do trees age on a microscopic level?
@Poshpaws certainly: Rando, T. A., & Chang, H. Y. (2012). Aging, rejuvenation, and epigenetic reprogramming: resetting the aging clock. Cell, 148(1-2), 46-57. doi:10.1016/j.cell.2012.01.003
Jul
21
comment How did the nucleobases in the Murchison meteorite form?
I've not read of complex molecules form in clouds before - are these molecules faithfully replicated in such a way as to call them living?
Jul
20
revised How did the nucleobases in the Murchison meteorite form?
spelling etc
Jul
20
revised How and when did a dedicated immune system evolve?
changed title - reads a bit better now
Jul
20
revised How did the nucleobases in the Murchison meteorite form?
added 49 characters in body; added 14 characters in body
Jul
20
asked How and when did a dedicated immune system evolve?
Jul
20
answered How did the nucleobases in the Murchison meteorite form?