3,485 reputation
11246
bio website
location
age
visits member for 2 years, 7 months
seen Oct 29 at 15:29

"Live a good life. If there are gods and they are just, they will not care how devout you have been, but will welcome you based on the values you have lived by. If there are gods, but unjust, then you should not want to worship them. If there are no gods, then you will be gone, but will have lived a noble life that will live on in the memory of your loved ones. I am not afraid."

  • Unknown

Jul
5
awarded  Enthusiast
Jul
4
revised Do gene expression levels necessarily correspond to levels of protein activation?
spelling
Jul
3
comment Paralogous genes in genome-wide association studies?
That is an interesting question (thanks for the expansion). If the paralogous genes were still functionally related there is likely to be redundancy between them, so a SNP in one of the copies may not manifest at all. A SNP that affects a sub-trait specific to one of the copies would need to have a massive effect (or the study would require a phenomonal sample size) to find it (unless it was a targeted study only on paralogous genes known to be disease related?). I don't know fo any studies, but will be interested in others answers!
Jul
3
comment Paralogous genes in genome-wide association studies?
Hello. Could you help by clarifying your question? Do you want to know whether paralogous genes/regions are over-represented in GWAS hits? It is an interesting hypothesis - have you any ideas/references why this may be the case? It's always best to give as full and clear a question as possible. Thanks
Jun
28
comment Is there any recent evidence for the aquatic ape theory of human evolution?
interesting - I have not heard this theory. Did you have links/references to this from your own reading?
Jun
27
revised variation in expression accounted for a SNP — what's a usual percent?
corrected a mistake and expanded a bit
Jun
27
comment Why does hair turn grey or white, and why does it happen later for some?
@RoryM - added reference to interesting review on the subject.
Jun
27
revised Why does hair turn grey or white, and why does it happen later for some?
updated and corrected
Jun
27
answered variation in expression accounted for a SNP — what's a usual percent?
Jun
27
answered Why does hair turn grey or white, and why does it happen later for some?
Jun
26
accepted Why do we grow so much hair on our heads compared to our bodies?
Jun
26
comment Could inhibition of progerin formation slow the rate at which a body ages?
@nico thanks - clarified in my post.
Jun
26
revised Could inhibition of progerin formation slow the rate at which a body ages?
clarified meaning as per nico's comment
Jun
26
comment Is Homo sapiens the only species capable of prioritization?
I think this is a tough question - how could you tell? Many animals are seemingly capable of 'planning' their lives (for instance mating and rearing offspring at the right time, keeping them fed, safe from predators, etc, might seem to have taken some planning) but that is not to say they do any such thing. I would have thought it's all instinct, but I look forward to any answers!
Jun
25
comment Could inhibition of progerin formation slow the rate at which a body ages?
A catalyst to what, and what pathway? If you mean aging, there is no 'aging pathway'
Jun
25
revised Could inhibition of progerin formation slow the rate at which a body ages?
actually the effect size isn't bad - changed my mind. But the significance is still nowehere near genome-wide.
Jun
25
comment Why do only only two sexes exist for animals?
I think the OP is likely asking why mammals only have 2 sexes. This is quite different to asking why we don't spontaneously change sex (as you quite rightly point out, the physiological changes required are too much). But what you don't touch upon is why there are no examples of 3 sexes, for instance, in mammals (that I know of) - I think this would then be a very complete answer.
Jun
25
answered Could inhibition of progerin formation slow the rate at which a body ages?
Jun
25
comment Why do we grow so much hair on our heads compared to our bodies?
Interesting! May we have kept hair on our heads to keep the sun from directly heating our brains? Bit off topic, but do you suppose the increased endurance running is simply that running on 2 legs is more efficient than using all 4?
Jun
20
comment When has an organism evolved enough to be called a new species?
Not a problem, as you say there is no definitive way to draw the line between species, but the line is much easier to draw in animals like a horse. Yours should be the 'correct' answer for this, as the title to the question is not about horses, but species as a rule (the horses were just an example). But therein lies the problem - using one definition (the 'classical' definition?) we can distinguish between 2 closely related animals, but this same definition is not adequate for other organisms. Is it possible to clarify your answer to include separate definitions for plants/animals/bateria?