11,722 reputation
939
bio website affymetrix.com/analysis
location Berkeley, CA
age 49
visits member for 1 year, 5 months
seen 2 hours ago
stats profile views 133

PhD structural biology. I do bioinformatics for Affymetrix in the SF bay area. Interested in systems / synthetic biology, expression analysis and machine learning.


2h
comment Experimental evidence for the selfish gene vs. the selfish individual
I agree with @ChinmayKanchi but its often said here that this is all proven. I haven't really found that myself - publications in reputable journals including Nature continue to appear. But maybe someone can post their full argument? @RichardSmith?
4h
answered What is in the space between neurons in a brain?
4h
revised Do forever-living organisms exist?
more reference
14h
comment Do male marsupials have a pouch?
...evolution can even make underwear!
1d
comment What medical and commercial proteins are made using genetically modified animals?
might well be right that this is the only current case. Transgenic animals are really expensive compared to transgenic bacteria - its very expensive to make a transgenic goat and the ability to produce the transgenic product often doesn't breed through - making you start all over again from scratch when the goats die.
1d
revised Amino acid characteristics that determine their chemical properties?
made title a question
1d
comment Is it possible to gain mutant powers through a genetically modified virus?
... if being dead is a mutant power, then certainly yes :)
1d
comment Has medical progress stopped human evolution?
As an example that we do change with evolution and a further Arnold reference, you can see that Neanderthals definitely were physically quite different from us. "Modern man a 'wimp'" : independent.co.uk/news/science/…
1d
comment Has medical progress stopped human evolution?
All this is not a simple question well tastes in what is attractive also changes. I'd say our appearance does and has changed over time, and this is because of sexual selection to a great extent. its a viable hypothesis, and there's evidence, but there are also definitely other forces in play here.
1d
revised Has medical progress stopped human evolution?
deleted 1 characters in body
1d
comment Has medical progress stopped human evolution?
Evolution is not entirely progressive - look up the 'red queen' on wikpedia. Competition changes traits by selection, but there is constant competition from the outside that reinforces change only for change's sake - it doesn't necessarily make the traits stronger. If you get the most masculine man and the most feminine woman, will the children have both extreme traits when and where you want them? Many exceptional trait combinations are not reproduced in offspring - they are as much coincidence as they are the product of selection. Look at pictures of Schwarzenegger Sons - not that big.
2d
answered Is there any source for raw data of SNP genotype frequency?
2d
comment copper spiral birth control not toxic?
It is toxic enough to disrupt reproduction which is relatively sensitive, but not enough to kill anyone. Still there are side effects that show up often.
2d
revised What could account for an apparent loss of mass at death?
added reference
2d
comment Primer design for Gibson assembly
Most vectors do have convenient cut sites, but I can see that this is convenient in a lot of ways and it would be quick to order new oligos for the vector. i really want to try this in the lab...
May
21
comment Recent and good quality articles on systems biology
I personally wish more sorts of questions like this were around more - having a good conversation about ongoing science is kinda hard to find on the internet...
May
21
comment Specifically What Protein Folding Calculations does Folding@Home do?
A starter: The old folding@home website has some starting links. The technique used is a form of molecular dynamics which basically simulates the protein chain atom by atom in an environment that sort of resembles water. there are other techinques to compute a protein fold, but don't require the computational power that folding@home has. folding.stanford.edu/English/Science
May
21
comment How did the activities of protocells become inheritable?
another side of the argument, which Richard Dawkins made is that replicators are necessary for selection. Sure other metabolizing and energy utilizing systems might have shown up, but those which replicate are the only ones you will see over time.
May
21
comment Primer design for Gibson assembly
it says can linearize the plasmid by cutting it and so you'd only need 2 primers to clone the insert. what advantage is there clone the vector as well? I guess it saves a miniprep, but 2 oligos cost more than a miniprep does..
May
20
comment Has medical progress stopped human evolution?
here's a post if not the primary reference. This sounds reasonable to me, though i'm sure its not completely proven. abc.net.au/news/2009-07-29/…