1,002 reputation
211
bio website
location Baltimore, MD
age 28
visits member for 2 years, 8 months
seen 10 mins ago

PhD candidate in the department of biophysics at Johns Hopkins.


17h
comment Is there any evolutionary advantage of selection of L-amino acid over D-amino acid?
@ChrisStronks And the mirror structure result would almost certainly be the same for any protein. A protein is the same as any other molecule in that if you flip all of the chiral centers you end up with its mirror image.
17h
comment Is there any evolutionary advantage of selection of L-amino acid over D-amino acid?
@ChrisStronks At least for enzyme activity, I think that the invariance of L- and D- follows from the fact that electromagnetic interactions don't change for a parity transformation (reflection is a type of parity transformation). So it would probably be the same for any enzyme.
20h
comment Mass spectrometry versus western blotting for validation
Ohhh, reviewers and their blots. I think that I have heard similar stories several dozen times now. Have you done replicates of the blots?
21h
comment Mass spectrometry versus western blotting for validation
Trying to answer any question other than "is this protein actually present in my sample" with a Western seems like a fool's errand. I think that it's completely reasonable to expect a large variability between your two methods.
1d
comment Hot water and bacteria
@DavidRicherby I changed the wording a little to reflect your comments, but I am curious about what you said. Do you have a reference?
1d
comment What is the biggest facultative anaerobic metazoan known to science?
The answer to your question is going to be some plant or fungus. You might want to stick the word "metazoan" somewhere in your question.
Dec
16
comment Use cases of RNA secondary structure prediction
@MadScientist citation, please? (good sir, etc)
Dec
16
comment What are the 5 most expensive machines that can be found in a bio-lab?
I actually like this question. @Chris is right that it depends on where you work, but I'm pretty sure the correct answer is synchrotron
Dec
7
comment Which three functional groups are found in the general structure of amino acids?
Your original statement of the question is a little bit lazy and lacking in background info. Please reword your question a little bit, and explain more of the background context and your own thinking on the matter, and then I'll update my answer, including the version of it that your professor was probably looking for in the first place.
Dec
7
comment Which three functional groups are found in the general structure of amino acids?
Homework question or no, it seemed interesting enough to merit an answer on this site. Also, having had a couple of hours to think about it the answer I gave is probably wrong, but out of deference to your concerns I won't correct it.
Dec
6
comment Is sexual selection evolutionarily advantageous?
If that's a direct, unqualified quote your biology teacher doesn't know what he's talking about.
Nov
13
comment Resource for finding what proteins bind?
"the question I am trying to answer is 'which proteins from list A interact with proteins from list B and vice-versa?'" You and every biophysicist on the planet.
Oct
31
comment What is the difference between embryology and developmental biology?
@terdon. Ha hah, all right. Honestly, I thought there was a reasonable possibility that you were an earnest seeker after truth
Oct
31
comment What is the difference between embryology and developmental biology?
@terdon they have zygotes. All multicellular organisms have at least some form of reproduction where their offspring pass through a single-cell or few-cell state (though I'm sure there's at least a few exceptions to this).
Oct
31
comment What is the difference between a phosphotransferase, a phosphatase, a phosphorylase and a kinase?
@canadianer That's true. My point was more about the futility of trying to define a short nomenclature for the set of all enzymes. Their complexity defies any simple classification. Save the jargon for when you have specifics to talk about, and talk about generalities in general terms.
Oct
31
comment What is the progressive evolutionary advantage that leads to flying?
@tryingToGetProgrammingStraight If you have a whole laundry list, try posting them here. Just maybe keep it to one a day.
Oct
31
comment What is the progressive evolutionary advantage that leads to flying?
@tryingToGetProgrammingStraight More seriously, it really depends on the organism/system in question. For example, the debate over why humans started walking upright has been a particularly acrimonious and silly one.
Oct
31
comment What is the progressive evolutionary advantage that leads to flying?
@tryingToGetProgrammingStraight Yes I do! BAHFest is truly an authoritative source for such information.
Oct
29
comment What is the H+ gradient in mitochondria?
@Sciiiiience An H+ ion is a proton
Apr
24
comment Has there ever been an attempt to create nutritionally tailored food for adult human consumption?
@Andrei Getting into the psychology side of it, the current consensus among researchers these days is that it takes about two months of daily repetition for a human to establish a behavior as a habit. At that point, even if the behavior is somewhat arduous/painful, it becomes more natural for the person to continue with it than to cease.