231 reputation
39
bio website
location
age
visits member for 2 years, 2 months
seen Jul 3 '12 at 13:44

Postgraduate student. University of Leeds UK. Statistical Epidemiology,


Mar
31
awarded  Notable Question
Nov
4
awarded  Notable Question
May
16
awarded  Popular Question
May
5
awarded  Yearling
Feb
23
awarded  Popular Question
May
18
comment What are the differences between white and brown adipose tissue?
but Kevin's answer on meta wasn't shot down, so I assumed it would be OK....
May
18
asked What are the differences between white and brown adipose tissue?
May
16
accepted obesity risk and single gene polymorphisms
May
16
awarded  Self-Learner
May
11
awarded  Teacher
May
11
answered obesity risk and single gene polymorphisms
May
9
awarded  Quorum
May
9
comment obesity risk and single gene polymorphisms
I think there are some statistical issues with this - such as multiple testing and family-wise error, but most of the studies in the meta-analysis I linked to seem to be quite solid and found odds ratios with confidence intervals comfortably above 1. Clearly it is well known that obesity etiology is multi-factorial and genetics plays a relatively smaller part (compared to the environment), but the evidence does seem clear that there are some genetic components, and gene-environment interactions are also likely.
May
8
asked obesity risk and single gene polymorphisms
May
8
comment Primary function of the enzyme lipoprotein lipase
+1 by the way :)
May
8
comment Primary function of the enzyme lipoprotein lipase
@Larry_Parnell Sorry, by writing "(adipocytes)" I meant to query whether the /primary/ function of LPL in adipose tissue is fat storage ? I took home from the answer is that LPL performs fat uptake and thereby facilitates fat storage.
May
8
awarded  Supporter
May
8
awarded  Scholar
May
8
accepted Primary function of the enzyme lipoprotein lipase
May
8
comment Primary function of the enzyme lipoprotein lipase
Great answer. Thank you ! I would upvote, but I don't have sufficient rep myself (yet). Just a further query: when I read: "facilitate fat uptake and storage" would I be right in saying the /primary/ function is fat uptake, which then results in fat storage (in adipocytes).