2,168 reputation
1936
bio website samilosoi.com
location Northern Europe
age 25
visits member for 3 years
seen 11 mins ago

Dec
5
comment Clonidine's adrenonergic nature?
So I propose that clonidine is not adrenomimetic but adrenolytic (i.e. adrenonergic and sympatholytic in one word). Do you agree? - Agonist mean to bind etc adrenoagonist to bind to adrenoreceptor. Mimetic means positive ANS effect and/or mimicing the behaviour of the stimuli from ANS. Adreno - just adrenoreceptor where the neurotransmitter is acetylcholine. Sympatho is about if the drug has sympathetic effect and its nature (sympathopositive (-mimetic) vs sympathonegative (sympatholytic i.e. decreasing concentration of acetylcholine etc in case of adrenoreceptor in a synapse)).
Dec
5
revised Clonidine's adrenonergic nature?
clearer
Dec
5
revised Fast standing and the heart's insufficient accommodation of the increased venous return
clearer and better thought
Dec
5
accepted To understand synthesis of e-NOS and n-NOS with respect to Ca and calmodulin
Dec
5
comment To understand synthesis of e-NOS and n-NOS with respect to Ca and calmodulin
Sorry, I cannot. This is a classroom discussion, mostly based on current textbooks in Physiology and Pathophysiology. Good bet would be in Robbins.
Dec
5
revised To define the total Resistance of Systemic Blood Circulation
edited tags
Dec
5
comment To define the total Resistance of Systemic Blood Circulation
We do not need to compare apples and cars. Linear case is straightforward. Thinking now the presented question. This applies necessary dependences and connections, mostly in electrophysiological level now.
Dec
5
comment To define the total Resistance of Systemic Blood Circulation
@Susan I really had a completely different target here for getting some nonlinear definition of the systemic vascular resistance. You will not find pieces of information about this in literature.
Dec
5
revised To define the total Resistance of Systemic Blood Circulation
this was what I was looking for - nonlinear definition of the total resistance
Dec
5
revised To define the total Resistance of Systemic Blood Circulation
rolled back to a previous revision
Dec
5
revised To define the total Resistance of Systemic Blood Circulation
rolled back to a previous revision
Dec
5
revised To define the total Resistance of Systemic Blood Circulation
typo
Dec
4
comment Are ipratropium and tolterodine parasympatholytic?
I think so too, but it would be great if source exists for this. I will write if I find one.
Dec
4
asked Are ipratropium and tolterodine parasympatholytic?
Dec
4
comment Theranos blood test's Specificity and Accuracy?
-1 I think your answer is too much business-minded: Extra value of device. Specificity and accuracy of the device in some test is very relevant here. I think you are little bit lost in your last big title question - PCR is for multiplying blood parts. Those patents seem to apply too it and to multiply just some parts of blood - see Noname's answer. Rheology of blood should be able to maintained by pharmacological methods and by method of educating personnel who take the blood. So no coagulation problems. I think your listed factors are not keys here. Those "other factors" are most relevant.
Dec
4
comment Differentiation of norepinephrine and epinephrine in indications
NE properties seem to go little over each other: its alphanergic properties cancel out some of its betanergic properties. This may result in the fact that epinephrine is more potent drug than norepinephrine. At least, it is used more widely and has more indications including PCR and acute anaphylaxis, in contrast to norepinephrine. I wonder if there are any indications of norepinephrine where you cannot use epinephrine. Probably, one such a property is acute hypotension. Probably some stability issue with the epinephrine or something.
Dec
4
accepted How can Pyridostigmine have the indication of Myasthenia?
Dec
4
comment How can Pyridostigmine have the indication of Myasthenia?
You are understanding me correctly. It seems that also the other short-acting and long-acting AChE are Nm and nicotinic besides neostigmine and pyridostigmine such as ipidacrine, donepezil and rivastigmine.
Dec
4
revised Differentiation of norepinephrine and epinephrine in indications
added 282 characters in body
Dec
4
asked Differentiation of norepinephrine and epinephrine in indications