2,172 reputation
1936
bio website samilosoi.com
location Northern Europe
age 25
visits member for 3 years
seen 9 hours ago

Dec
5
revised To define the total Resistance of Systemic Blood Circulation
typo
Dec
4
comment Are ipratropium and tolterodine parasympatholytic?
I think so too, but it would be great if source exists for this. I will write if I find one.
Dec
4
asked Are ipratropium and tolterodine parasympatholytic?
Dec
4
comment Theranos blood test's Specificity and Accuracy?
-1 I think your answer is too much business-minded: Extra value of device. Specificity and accuracy of the device in some test is very relevant here. I think you are little bit lost in your last big title question - PCR is for multiplying blood parts. Those patents seem to apply too it and to multiply just some parts of blood - see Noname's answer. Rheology of blood should be able to maintained by pharmacological methods and by method of educating personnel who take the blood. So no coagulation problems. I think your listed factors are not keys here. Those "other factors" are most relevant.
Dec
4
comment Differentiation of norepinephrine and epinephrine in indications
NE properties seem to go little over each other: its alphanergic properties cancel out some of its betanergic properties. This may result in the fact that epinephrine is more potent drug than norepinephrine. At least, it is used more widely and has more indications including PCR and acute anaphylaxis, in contrast to norepinephrine. I wonder if there are any indications of norepinephrine where you cannot use epinephrine. Probably, one such a property is acute hypotension. Probably some stability issue with the epinephrine or something.
Dec
4
accepted How can Pyridostigmine have the indication of Myasthenia?
Dec
4
comment How can Pyridostigmine have the indication of Myasthenia?
You are understanding me correctly. It seems that also the other short-acting and long-acting AChE are Nm and nicotinic besides neostigmine and pyridostigmine such as ipidacrine, donepezil and rivastigmine.
Dec
4
revised Differentiation of norepinephrine and epinephrine in indications
added 282 characters in body
Dec
4
asked Differentiation of norepinephrine and epinephrine in indications
Dec
4
comment Theranos blood test's Specificity and Accuracy?
Please, see Noname's answer. I think you need to revise your answer accordingly.
Dec
4
comment How can Pyridostigmine have the indication of Myasthenia?
Thank you for your excellent answer with great details! It is never wrong to repeat. Pyridostigmine is parasympathomimetic and reversible cholinesterase inhibitor. These two features seem to work in different directions, but the latter is the main one. It leads to the property of reversing muscle relaxants and its indication of myasthenia gravis. The former effect does not seem to be a major one. -- Let's consider Pilocarpine which is cholinomimetic and exclusively muscarinic (nothing about nicotinic?). It seems that only acetylcholine inhibitors are exclusively nicotinic with (N1 or Nm).
Dec
4
revised Theranos blood test's Specificity and Accuracy?
one mistake in body fixed
Dec
4
comment Theranos blood test's Specificity and Accuracy?
Thank you very much for your excellent answer with outstanding details and analysis! I am interested in in the Biological and Physical limitations here, particularly. They do not cover anywhere the uncertainties of their tests. I would like to work for a review about uncertainties in sampling small volumes of blood in different tests. How did you find the pieces of information about their patents? Google patents with Theranos gives 10 international classifications: A61B5/00, A61M5/172, B01J19/00, A61B5/15, B01L3/00, A61M5/142, A61M37/00, A61M5/145, G01N35/00 which I think are their patents
Dec
3
asked How can Pyridostigmine have the indication of Myasthenia?
Dec
3
revised Theranos blood test's Specificity and Accuracy?
deleted 4 characters in body
Dec
3
revised Theranos blood test's Specificity and Accuracy?
added 35 characters in body
Dec
3
asked Theranos blood test's Specificity and Accuracy?
Dec
2
comment To understand side-effects for nebivolol's beta1 selective pathway in PubChem?
US is enough, since I need to follow AAMI standards in my work that means US is the best choice. Thank you for the comment! Is this the resource which you use pdr.net ?
Dec
2
revised To understand side-effects for nebivolol's beta1 selective pathway in PubChem?
one place to to look added
Dec
2
comment To understand side-effects for nebivolol's beta1 selective pathway in PubChem?
SmPCs are Summaries of Product Characteristics found in most packages of drugs. Here is European guideline for them ec.europa.eu/health/files/eudralex/vol-2/c/…