2,625 reputation
627
bio website mattdmo.com
location near Boston
age 35
visits member for 1 year, 10 months
seen 3 hours ago

Long-time OSS user/admin, intermediate coder - I heart . Master of Science in Molecular Medicine, many years' experience in biotech working with antibodies and cell-based assays. Science and computer geek. Dad.


Do you love Sublime Text? Looking for a color scheme that looks good in lots of languages and takes advantage of as many scopes as possible? Check out Neon Color Scheme, available through Package Control and hosted on GitHub. Also works great in TextMate and TextMate 2 - instructions in the README.


Looking for a great Linux hosting provider geared toward developers with shell access, a bunch of ready-to-deploy apps, and awesome tech support? Check out WebFaction, my favorite alternative to the big hosting beasts. They run CentOS 6 x64, have datacenters around the world, and have a full suite of regularly-updated development and deployment tools. And did I mention they're cheap? My basic plan with 512MB RAM, 100GB disk, and 600 GB bandwidth/month is just US$8.50/mo! (if you prepay for a full year - US$102). Check out all these other features:

  • Full control over shell access (multi-user capability), email, and DNS.
  • Extensive, searchable, useful documentation.
  • Python, Ruby/Rails, PHP, Java, Perl, shell scripts...
  • Ability to install whatever software tools you need, and execute long-running processes.
  • nginx and Apache, MySQL, PostgreSQL, SQLite, MongoDB...
  • "One-click" (actually, several clicks and some typing) installers for a whole bunch (and different versions) of popular applications like Django, Rails, WordPress, Joomla, Drupal, Git, Redmine, and more.
  • and a ton of other stuff. Just follow the link!

I honestly don't know of any other hosting provider that has a similar product, and if one exists I can't imagine it's as cheap. BTW, I don't work for them, I'm just a very satisfied customer.


Why Pigimal?

I sometimes call my guinea pig (also known as a cavy) "Pigimal", which is short for "Piggy Animal." Now you know.


Flair, Baby!


Apr
13
revised Why mosquito bite is confined to a certain shape?
edited tags
Apr
9
reviewed No Action Needed Why are there ecosystems?
Apr
9
reviewed No Action Needed Why are there ecosystems?
Apr
9
reviewed No Action Needed Why doesn't the sperm die if there is citric acid and acid phosphatases in the semen?
Apr
9
reviewed Reviewed Which disorders are fully concordant?
Apr
9
comment Which disorders are fully concordant?
For those that don't know about it, could you expand a little on what MZ discordance is and what it means for a disease?
Apr
2
comment dopamine paradox in Schizophrenia
I'm no expert, which is why this isn't an answer, but it may have to do with receptor down-regulation, or an altering of receptor signaling.
Apr
1
comment How does mutation work natural population? and is it common in protists or prokaryotes?
What other causes of evolutionary change are you comparing mutations to? If you get right down to it, every change is a mutation of some sort...
Apr
1
reviewed No Action Needed Exotic Cell Shapes
Apr
1
reviewed Close Cloning a gene of an organism with an nonsequenced genome
Apr
1
reviewed Close What is the possibility of retinal damage from light flashes?
Apr
1
reviewed Close Banana-only diet for humans
Mar
31
comment Cells created using differently aligned proteins
@nico - a few D-amino acids here and there may not affect structure/function too much, I agree. But I really can't imagine that a fully D organism could exist. I didn't get into this in my answer, but I doubt that all tRNAs could bind the D isoforms of their respective payloads. Secondary and tertiary structures often depend on H-bonding, and a change in chirality could destroy those bonds, leading to incorrect folding.
Mar
31
awarded  Strunk & White
Mar
31
revised Brainbow fluorescence labeling technique
added 15 characters in body
Mar
30
answered Cells created using differently aligned proteins
Mar
30
comment building intelligent structure with random evolution requires series of non useful steps
Unfortunately, evolution is not like writing a computer program, which has a very strict syntax, type checking, etc. Please read through the comments and answers to this recent question for a more in-depth discussion. This response in particular addresses the computer analogy. "Advantageous" is a tricky word. There are plenty of instances of DNA changes ("mutations" if you like) that may be negative in the short run, but prove protective otherwise. Sickle-cell anemia is one of those.
Mar
30
answered Can inhibition of lymphocytes migration be a direct cause of chronic inflammation?
Mar
30
comment Can inhibition of lymphocytes migration be a direct cause of chronic inflammation?
I edited your question both to add your image of the slide and to remove your "quote", which was not at all what the slide said. Also, it should be clarified here that cord factor comes from M. tuberculosis.
Mar
30
revised Can inhibition of lymphocytes migration be a direct cause of chronic inflammation?
added image inline, removed quote (since it wasn't an exact quote at all)