3,759 reputation
931
bio website mattdmo.com
location near Boston
age 36
visits member for 2 years, 6 months
seen 11 hours ago

Long-time OSS user/admin, intermediate coder - I heart . Master of Science in Molecular Medicine, many years' experience in biotech working with antibodies and cell-based assays. Science and computer geek. Dad.


Do you love Sublime Text? Looking for a color scheme that looks good in lots of languages and takes advantage of as many scopes as possible? Check out my Neon Color Scheme, available through Package Control. Also works great in TextMate.

Also, check out Python Improved, a better, updated Python .tmLanguage syntax definition for Sublime and TextMate. Fixes lots of bugs with the existing syntax, and adds new scopes for IPython, Django, Python 3 support, and much more. Use Neon for customized syntax highlighting, or modify your favorite color scheme.


Looking for a great Linux hosting provider geared toward developers with shell access, a bunch of ready-to-deploy apps, and awesome tech support? Check out WebFaction, my favorite alternative to the big hosting beasts. They run CentOS 6 x64, have datacenters around the world, and have a full suite of regularly-updated development and deployment tools. And did I mention they're cheap? My basic plan with 512MB RAM, 100GB disk, and 600 GB bandwidth/month is just US$8.50/mo! (if you prepay for a full year - US$102). Check out all these other features:

  • Full control over shell access (multi-user capability), email, and DNS.
  • Python, Ruby/Rails, PHP, Java, Perl, shell scripts...
  • Ability to install whatever software tools you need, and execute long-running processes.
  • nginx and Apache, MySQL, PostgreSQL, SQLite, MongoDB...
  • "One-click" (actually, several clicks and some typing) installers for a whole bunch (and different versions) of popular applications like Django, Rails, WordPress, Joomla, Drupal, and more.
  • and a ton of other stuff.

I honestly don't know of any other hosting provider that has a similar product, and if one exists I can't imagine it's as cheap. BTW, I don't work for them, I'm just a very satisfied customer.


Why Pigimal?

I sometimes call my guinea pig (also known as a cavy) "Pigimal", which is short for "Piggy Animal." Now you know.


Flair, Baby! null @ Miaou


1d
comment Binding of Multivalent Antibody to mutiple epitopes?
Please separate this into two questions.
1d
comment Persistency of botulinum toxin in environment
Please add some references to your answer.
2d
comment what makes different materials to have different tastes?
Have you read the Wikipedia article on taste? If not, please do so. If so, what specifically about it didn't you understand?
2d
comment Why do the major and minor groove exist in DNA?
Have you read the articles on DNA, nucleic acid tertiary structure, and the structure of a nucleic acid double helix? They all talk about DNA structure and should be quite informative.
Dec
13
comment PCR, writing methods section for a journal, I am quite inexperienced in writing, and was just checking in if this is okay
@Barbara Stack Exchange sites, including Biology, are not forums. They are question-and-answer sites, where specific questions are asked and specific answers (where possible) are given. "Forum" implies discussion and questions that can be open-ended or opinion-based (What do you think about this?), all of which are off-topic here.
Dec
12
comment How can site-directed mutagenesis be used to suppress the production of anti-antibodies?
Could you link to your previous post for context? Site-directed mutagenesis is nearly impossible to perform in vivo, so I'm wondering what the comment poster was getting at...
Dec
11
comment Would my hands sweat this much if I wasn't wearing gloves?
Thanks for the answer, I had kind of forgotten about this question. It's too bad there hasn't been any work done on local temps, because I suspect that's why this happens - the gloves are somewhat insulating and there's no opportunity for evaporation, therefore raising the local temperature and causing a positive feedback loop. I guess I'll have to read up more on sweating disorders, as I tend to be rather... shall we say... damp frequently, but that's OT for here unless I anonymize it :)
Dec
11
comment Would my hands sweat this much if I wasn't wearing gloves?
To the (potential) close-voters: This is not a medical question (I'm not asking for medical advice, I'm simply describing a phenotype). This isn't (or shouldn't be) primarily opinion-based, because I'm not asking for opinions, I'm asking if there is a clear, biological explanation for this. If you happen to disagree, please leave a comment and I'll try and clean up the wording.
Dec
10
comment What is the origin of DNA?
@GoodGravy the meta discussion is here. The consensus seems to be that these type of questions should be closed as Too Broad, not homework, as the OP isn't necessarily doing homework, they're just not doing basic background research.
Dec
7
comment Can a human acquire a memory of an animal?
@ShadowRealm if this answered your question, please indicate as such by clicking the check mark next to it (it will turn green). Please see What should I do when someone answers my question? for more details.
Dec
7
comment Increasing/decreasing signal intensity in Western blotting
@Fistula I worked for an antibody company for over 6 years doing antibody preparation, QC, and tech support, so this answer is just a quick distillation of my knowledge. I can talk for hours about Westerns, if you're so inclined :)
Dec
7
comment Which three functional groups are found in the general structure of amino acids?
as long as the answer is here, you may as well correct it. I also agree that the question is interesting, all I was trying to say is that ideally, you want to get the OP to think about their problem a little bit. Suggest that they edit their question to describe what they've already tried. Some people are genuinly stuck, and it's fine to help them, but it's best to try and get some more info out of them first.
Dec
7
comment Can rapid eye blinking induce epileptic seizures?
@ChrisStronks reopened for your pleasure.
Dec
7
comment Which three functional groups are found in the general structure of amino acids?
Please read our homework policy before answering questions such as this. We should not be giving out free answers to students who have not even done the most rudimentary thinking about their problem. This doesn't help them learn at all. Instead, I would recommend that you leave a comment asking for which groups they've already come up with, wait for an answer, and then ask them to think about the central carbon, and see if they can come up with the answer themselves. Spoon-feeding direct answers is not terribly helpful.
Dec
2
comment human anti-mouse antibody
@GriffinEvo see this meta post for a previous discussion on the phenomenon, and of course this recent related post as well. Regarding the (now-deleted) answer-as-comment here, it was probably 6 or 7 lines long, and covered all the points in the answer below, with the exception of the alignment.
Dec
2
comment human anti-mouse antibody
@user137 please don't answer questions in comments. Write a full answer instead.
Dec
2
comment Why only female mammals have well developed mammary glands?
I just added [citation needed] to the WP article's sentence in question.
Dec
1
comment How to manage fat-gluten oxidation in celiac disease?
Do you have any evidence that gluten is stored in fat cells? As far as I know, it can only be synthesized by certain plants...
Nov
27
comment How do gory images lead to nausea?
This does not provide an answer to the question. To critique or request clarification from an author, leave a comment below their post.
Nov
24
comment plot the nucleosome distance to TSS
This question appears to be off-topic because it is about programming. It should be asked at Stack Overflow or Biostars.