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bio website mattdmo.com
location near Boston
age 36
visits member for 2 years, 4 months
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Long-time OSS user/admin, intermediate coder - I heart . Master of Science in Molecular Medicine, many years' experience in biotech working with antibodies and cell-based assays. Science and computer geek. Dad.


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2d
comment About the plight of Elephants and efforts to conserve them?
Nice story. What is your question?
2d
comment MRI with lots of white matter.
Why are you asking? Personal medical questions are off-topic for Biology.SE, as we cannot safely provide medical advice.
2d
comment Nystagmus drug FDA approval?
googling for the drug name will tell you if it's available. Based on my 4 seconds of research, the first two are.
2d
comment When we vomit how are the contents transferred to stomach/esophagus?
Blood cannot be detoxified by vomiting - that's the job of the liver and kidneys. There is no "reverse transport" from bloodstream to stomach - it all goes the other way. Vomiting mainly serves to remove irritants from the stomach.
Oct
16
comment Questions related to immunity
As I (and likely others) have suggested to you in the past, please find an introduction to immunology textbook, and read it. Many of the questions you ask here are very basic topics in the field, and you should be trying to educate yourself instead of asking others to do the explaining for you. If possible, sign up for an immunology class at your local college/university, or look for lectures online.
Oct
12
comment Visualizing GFP in transgenic rice seeds?
395 nm is not quite UV, so if you're not getting a strong enough signal (depending on the exact wavelength your transluminator emits, and the excitation profile of your protein), you could try using a purple light bulb. You can sometimes find them in big-box home centers like Home Depot, Lowes, etc., and you should also be able to find them at party stores. BTW, are you using GFPuv?
Oct
12
comment Preservation of human tissue
I would assume you're using gloves to handle them?
Oct
8
comment Does drinking spoiled milk that has been boiled upset the GI tract?
Toxins could be produced by the bacteria that spoiled the milk that wouldn't be destroyed by boiling. Similarly, spores could be formed that are impervious to boiling as well.
Oct
5
comment Why does K+ have more concentration inside of the cell compared to outside of the cell? Why is Na+ and Cl- the opposite?
Is this a homework question?
Oct
5
comment Whats the difference between voltage gated and ligand gated neurons?
Is this a homework question? If so, please read our homework policy. Essentially, we require that you attempt to answer your own question as much as possible, explaining your thinking on the matter and where you are stuck. We will not answer homework question without any effort on the questioner's part.
Oct
2
comment Can you get enough water by eating only fish?
small hole in your scenario - if you can cook fish, you should be able to boil seawater and condense the steam for desalinated water :)
Oct
1
comment Which types of blood vessels can regenerate in humans/mammals?
Is this by chance a homework question? If so, please read our homework policy. Essentially, we ask you to try and answer as much of the question yourself as you can, and put down your thinking on the parts you're not sure about.
Oct
1
comment Can you disconnect sensation from the brain without destroying muscle functions?
@user137 Leprosy is a disease primarily of the peripheral nerves, while nerves responsible for motion are often deeper. However, like I said the two tend to become bundled closer together the closer to the trunk (and spine) you get. I just don't think it would be plausible to selectively block sensory neurons without affecting motor neurons as well.
Sep
30
comment Can you disconnect sensation from the brain without destroying muscle functions?
It's possible to block hearing, or sight (especially sight- just block the optic nerve), but destroying feeling in the body would be neigh-on impossible without completely paralyzing someone. The nerves for muscle control and sensation are bundled very close to each other the farther up the extremity you go, and by the time you get to the spinal cord they're all mashed in there together.
Sep
30
comment What percent of your blood can you lose before you need a transfusion
@anongoodnurse I agree.
Sep
29
comment What percent of your blood can you lose before you need a transfusion
@anongoodnurse a significant drop in blood pressure, along with a commensurate increase in heartrate, is often used as a "back of the envelope" measure of blood loss.
Sep
28
comment Safety of cobalt-chromium and nickel-chromium dental implants
Alloys have completely different chemical properties than their component elements. Elemental mercury is liquid, and is toxic, but when alloyed into amalgam it is perfectly safe, and has been used in dental fillings for a very long time with no negative effects. The same is true of cobalt and chromium alloys - they are chemically bonded to the other elements in the alloy, making a new molecule, and cannot "leach out" without the chemical bonds being broken, which cannot happen in the mouth or at standard cooking temperatures. Hence, they are safe for food prep and for fillings/implants.
Sep
28
comment Is carbohydrate an important part of phospholipid?
Similar question: what are the elements in glycerol?
Sep
25
comment What is a catalytic domain of an enzyme?
Quick answers: yes, and it varies tremendously. Enzymes catalyze a huge variety of reactions, from cutting DNA to adding amino acids to a growing polypeptide chain, to breaking down complex sugars, and many more besides. Catalytic domains vary from enzyme family to family, and even between enzymes in a single family. There really is no generalization you can make about structure or function, as it is so different from one to another.
Sep
21
comment Distance matrix with different length sequences
Without seeing your code it's kind of hard to help. This question is much more suited for Stack Overflow, please ask it over there and tag it [python] and [biopython].