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bio website mattdmo.com
location near Boston
age 36
visits member for 2 years, 1 month
seen 3 hours ago

Long-time OSS user/admin, intermediate coder - I heart . Master of Science in Molecular Medicine, many years' experience in biotech working with antibodies and cell-based assays. Science and computer geek. Dad.


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May
29
comment Implications of what the discovery of Naia means
As far as I can remember from skimming the published paper, it does provide support to the hypothesis that the first Americans probably migrated over a Bering Strait land bridge sometime during the last ice age. Remember, individual scientific findings rarely "prove" anything, they just support or refute a certain hypothesis (what a layman would call a "theory", a word which has a rather different meaning when used by scientists).
May
26
comment Breathing under water
@Superbest - I would imagine that great white sharks consume a lot of oxygen when they're hunting, and last time I saw one it was just slightly larger than I am :)
May
26
comment How are Maggots Sterilized (Disinfected)?
They are grown in the same way that "clean" mice that don't have any gut flora are grown - originally they came from the wild, were cleaned, then kept in specific conditions after that. The first couple generations may be iffy, but dirt isn't inheritable...
May
26
comment Genes, chromosomes, base pairs and the 23 pairs
The Wikipedia articles for chromosomes, genes, and DNA contain all the information you need, and are literally the first links of the respective Google searches for those words.
May
26
comment Genes, chromosomes, base pairs and the 23 pairs
Pet peeve of mine - chromosomes are not X-shaped! They only look like that at one particular point in mitosis, and not even at the point where they make karyotypes. Sorry, nothing wrong with your answer, I just had to vent :)
May
26
comment Meaning of “auto” in trans autophosphorylation?
OP may not see your comment if you don't @mention him... :/
May
12
comment What is a suicide plasmid?
Check out this page - it has a long discussion of suicide vectors, and from the note at the bottom it was adapted from a published source.
May
6
comment How to convince suspension cells to adhere more tightly?
Interesting. I'll have to check them out a little more. I'm not developing the assay anymore (I posted the question a year ago), but I ended up switching platforms to flow cytometry, and just used round-bottom/v-bottom plates.
May
6
comment What kind of bird species is this?
Thank you for your answer. In the future, please do not use URL shorteners like goo.gl for your links - there is no text limit on answers, redirection schemes may not last forever, and the simple fact that you're obscuring the URL may lead readers to think that you're trying to hide something like a spam site.
May
6
comment About virus developement
Just like other organisms, viruses don't just spontaneously "appear" out of nowhere. They evolve from earlier viruses. They can't just "pop out" of the DNA of another species.
May
2
comment Help explain multi alleles in terms of actual genetic code
@user1357015 not at a single point, because there are only 4 bases in DNA. However, any one gene may have from a few to hundreds of SNPs, each one creating a separate "allele."
May
2
comment What are the Gateway clonase enzymes?
I would imagine that if they're not listed on the datasheet, you're not going to be able to find out what they are...
May
1
comment About a mechanical aid to the heart
@user128932 - you can have an implanted assistive device that helps by pumping some of, but not the entire, volume of blood. These are used by patients (and I assume this young girl is one) whose hearts can still pump blood on their own, but for whatever reason are unable to do it under optimal conditions (low pressure and/or low volume caused by incomplete chamber contraction/expansion, backflow from issues like leaky valves, etc.).
May
1
comment Enzyme kinetics
A basic biochemistry textbook (or Google) will be very useful in answering this.
May
1
comment What is most simple eukaryotic genome?
you can synthesize DNA of any length, from 1 bp on up, so this question is kind of meaningless...
Apr
27
comment How does a person get AIDS?
It is not entirely correct that a "person carrying the HIV virus is suffering from AIDS." HIV (Human Immunodeficiency Virus Type 1) is the virus that causes the disease known as AIDS (Acquired Immune Deficiency Syndrome). People can be carrying the virus and yet not displaying any of the symptoms of AIDS, at various timepoints from the point of infection, not just in the very beginning. It is much more scientifically/medically correct to refer to one's status as HIV-positive or HIV-negative, thanks to the amazing anti-viral drugs now on the market.
Apr
26
comment Are people genetically predisposed to being interested in specific fields/ideas? How does specialization occur?
Have there been any "separated twin" studies on this? Although, speaking from informal experience, several of the twin sets I know are in completely different lines of work, if that's any measure of "interest."
Apr
9
comment Which disorders are fully concordant?
For those that don't know about it, could you expand a little on what MZ discordance is and what it means for a disease?
Apr
2
comment dopamine paradox in Schizophrenia
I'm no expert, which is why this isn't an answer, but it may have to do with receptor down-regulation, or an altering of receptor signaling.
Apr
1
comment How does mutation cause natural selection? and is it common in protists or prokaryotes?
What other causes of evolutionary change are you comparing mutations to? If you get right down to it, every change is a mutation of some sort...