Timeline for Why is cyanide poisonous?

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Dec 15 '13 at 12:03 history edited Mad Scientist
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Dec 14 '13 at 19:57 answer krushna timeline score: 2
Dec 14 '13 at 14:32 comment added MattDMo all these comments could be incorporated into answers - please don't answer questions in comments!
Dec 14 '13 at 13:44 history tweeted twitter.com/#!/StackBiology/status/411854204354191360
Dec 14 '13 at 9:15 comment added stochastic13 That leakage is due to the inefficiency of the complex-specificity, i.e. sometimes the highly specific requirement of substrate for these electron-transfer enzymes relaxes and it allows some electrons to leak, forming free ionic oxygen radicals. Otherwise, they are very specific in what they reduce and hence cannot bypass the predetermined chain disabling the effect of cyanide.
Dec 14 '13 at 4:22 comment added Tyler But that doesn't explain why the electrons have to be passed to complex IV. My question is why can't they bypass that complex if it's deactivated and just go straight to oxygen? From what I understand, premature electron leakage toward oxygen is one of the reasons cells don't produce ATP at the theoretical maximum efficiency.
Dec 14 '13 at 4:13 comment added user560 Electrons get stuck because they can't be passed to complex IV, and this causes a backup in all the complexes of the electron transport chain. Therefore the cell faces an energy crisis, and eventually causes death.
Dec 14 '13 at 4:10 review First posts
Dec 14 '13 at 7:01
Dec 14 '13 at 3:51 history asked Tyler CC BY-SA 3.0