Timeline for does order of genes in a chromosome matter?
Current License: CC BY-SA 3.0
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| Jul 9, 2014 at 22:13 | comment | added | terdon | That's kind of cheating though. Most cancer-causing translocations are either because their insertion causes frameshifts that disable other genes or because, as in your example, regulatory elements are left out. The modern definition of a gene tends to include its regulatory elements so here, you're not changing the order of the genes but breaking them up which is a whole different thing. I can't think of any cases where the order of the genes itself is important (in eukaryotes anyway, barring operons and the like) and would be quite interested to know of any. | |
| Jul 9, 2014 at 17:32 | vote | accept | user813801 | ||
| Jul 10, 2014 at 8:01 | |||||
| Jul 8, 2014 at 20:24 | history | edited | Chris♦ | CC BY-SA 3.0 |
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| Jul 8, 2014 at 20:15 | history | edited | Chris♦ | CC BY-SA 3.0 |
added 346 characters in body
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| Jul 8, 2014 at 20:04 | history | answered | Chris♦ | CC BY-SA 3.0 |