Timeline for What is the purpose of gluconeogenesis?
Current License: CC BY-SA 3.0
10 events
| when toggle format | what | by | license | comment | |
|---|---|---|---|---|---|
| Apr 8, 2015 at 10:41 | comment | added | Chris♦ | @AliceD In a way, we are both right. Odd chain fatty acids can be oxidized to propionyl-CoA which is then converted into succinyl-CoA and further into pyruvate, which can enter the glucneogenesis pathway. Even chain fatty acids are oxidized to Acetyl-CoA which enters the TCA cycle but cannot be used for making glucose. It's good to have the thick biochemistry books at hand :-) | |
| Apr 8, 2015 at 10:38 | history | edited | Chris♦ | CC BY-SA 3.0 |
added 19 characters in body
|
| Apr 8, 2015 at 6:21 | comment | added | Chris♦ | I will make the answer clearer later today. | |
| Apr 8, 2015 at 5:56 | comment | added | AliceD♦ | I thought the backbone of the glucose as the end product is not structurally related to fatty acids, but to the substrate of GNG such as amino acids. As the answer is formulated it reads like fatty acids are converted to glucose, which is not the case. I thought an essential feature of metabolism in general was that sugars can be converted to fatty acids, but not the reverse. Hence the problems people have to reduce bodily fat. GNG doesn't take fatty acids in as a substrate. Correct me if I am wrong. | |
| Apr 8, 2015 at 5:32 | comment | added | Chris♦ | @AliceD Fatty acids are no direct source for gluconeogenesis, but where does the necessary Acetyl-CoA come from? For example from the beta-oxidation of fatty acids. | |
| Apr 8, 2015 at 1:33 | comment | added | AliceD♦ | fatty acids are not a substrate for gluconeogenesis. | |
| S Apr 7, 2015 at 23:59 | history | suggested | CrypticLogic | CC BY-SA 3.0 |
Corrected Spelling of Gluconeogenesis and glucose
|
| Apr 7, 2015 at 23:09 | review | Suggested edits | |||
| S Apr 7, 2015 at 23:59 | |||||
| Apr 7, 2015 at 17:11 | vote | accept | Paze | ||
| Apr 7, 2015 at 16:48 | history | answered | Chris♦ | CC BY-SA 3.0 |