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Jan 1, 2019 at 21:12 comment added David Just updated as promised. To try to make the argument easier to follow I relegated certain points to footnotes. Happy to be informed of any typos or mistakes.
Jan 1, 2019 at 21:10 history edited David CC BY-SA 4.0
Revised in view of comments by poster and user1136
Dec 31, 2018 at 10:19 comment added Sully Chen This is amazing, exactly what I was wondering!
Dec 31, 2018 at 10:19 vote accept Sully Chen
Dec 31, 2018 at 9:29 comment added David @user1136 — Thanks for that — have downloaded the paper and will read it. Sounds the sort of thing that must have been discussed in TIBS at some stage. It is interesting in that it would provide less reversible phosphodiester bond formation without the hydrolysis of pyrophosphate, which one might suppose developed subsequently in evolution to lock things down. I'll revise my answer when I have a moment.
Dec 30, 2018 at 16:20 history answered David CC BY-SA 4.0