2
$\begingroup$

In the cell cycle (G1-S-G2-M), all of the DNA is replicated during the S or Synthesis stage. The cell may then spend some considerable time in the G2 phase before splitting in the M phase. Since there is double the amount of genetic material in the G2 phase, what mechanism if any, prevents the amount of gene expression from also doubling?

$\endgroup$

1 Answer 1

1
$\begingroup$

When the double strand is duplicated, the old strand (or, in other terms, the template) is methylated : this modification is enough to prevent the bind by the RNApol system and, by so, the transcription. By methylation, DNA-repair systems are able to detect which is the newer strand, to discover and fix replication errors.

Here you can find additional infos

$\endgroup$

You must log in to answer this question.

Not the answer you're looking for? Browse other questions tagged .